Compounds That Target CDK12

Cyclin-dependent kinase 12 · 68 compounds in BiohacksAI corpus

CDK12 (Cyclin-dependent kinase 12) is a protein kinase involved in intracellular signal transduction. Kinases phosphorylate downstream substrates to regulate cell growth, survival, and metabolism. The 68 compounds targeting CDK12 include both pharmaceutical inhibitors and natural compounds with evidence of kinase modulation, ranked by evidence strength from the BiohacksAI corpus.

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Most Studied Compounds for CDK12

Allium Sativum

500+

studies

Juglans Regia

500+

studies

Centella Asiatica

499+

studies

Foeniculum Vulgare

499+

studies

Panax Ginseng

300+

studies

Rubia Cordifolia

200+

studies

All 50 Compounds — Ranked by Evidence

Alvocidib

4.52

confidence

Dinaciclib

3.87

confidence

Fasudil

3.66

confidence

Bms 387032

3.47

confidence

At 7519

3.33

confidence

Zotiraciclib

2.56

confidence

Defactinib

2.48

confidence

Rg 547

2.08

confidence

Amg 900

2.08

confidence

Istisociclib

2.08

confidence

Artemisia Argyi

1.00

confidence

Chaenomeles Speciosa

1.00

confidence

Dimocarpus Longan

1.00

confidence

Morus Alba

1.00

confidence

Panax Ginseng

300+

studies

1.00

confidence

Rubia Cordifolia

200+

studies

1.00

confidence

Scutellaria Baicalensis

1.00

confidence

Smilax Glabra

1.00

confidence

Vigna Umbellata

1.00

confidence

Agastache Rugosa

0.50

confidence

Alisma Plantago

0.50

confidence

Allium Sativum

500+

studies

0.50

confidence

Allium Tuberosum

0.50

confidence

Aloe Vera

0.50

confidence

Apis Mellifera

0.50

confidence

Aquilaria Sinensis

0.50

confidence

Arctium Lappa

0.50

confidence

Atractylodes Macrocephala

0.50

confidence

Aucklandia Lappa

0.50

confidence

Belamcanda Chinensis

0.50

confidence

Bupleurum Chinense

0.50

confidence

Carthamus Tinctorius

0.50

confidence

Centella Asiatica

499+

studies

0.50

confidence

Citrus Reticulata

0.50

confidence

Cnidium Monnieri

0.50

confidence

Commiphora Myrrha

0.50

confidence

Cuscuta Chinensis

0.50

confidence

Ephedra Sinica

0.50

confidence

Eriobotrya Japonica

0.50

confidence

Eucommia Ulmoides

0.50

confidence

Foeniculum Vulgare

499+

studies

0.50

confidence

Fritillaria Cirrhosa

0.50

confidence

Gastrodia Elata

0.50

confidence

Glycine Max

0.50

confidence

Inula Japonica

0.50

confidence

Juglans Regia

500+

studies

0.50

confidence

Ligusticum Chuanxiong

0.50

confidence

Lobelia Chinensis

0.50

confidence

Lonicera Japonica

0.50

confidence

Mosla Chinensis

0.50

confidence

The compounds above were identified through computational analysis of BindingDB binding assay data and PubMed literature for CDK12 (Cyclin-dependent kinase 12). Confidence scores reflect the strength and breadth of experimental evidence.

Explore related resources: CDK12 target overview · All biological targets · Biological pathways

Data from BindingDB and PubMed. For research purposes only. Not medical advice.