Compounds That Target CDK16

cyclin dependent kinase 16 · 128 compounds in BiohacksAI corpus

CDK16 (cyclin dependent kinase 16) is a protein kinase involved in intracellular signal transduction. Kinases phosphorylate downstream substrates to regulate cell growth, survival, and metabolism. The 128 compounds targeting CDK16 include both pharmaceutical inhibitors and natural compounds with evidence of kinase modulation, ranked by evidence strength from the BiohacksAI corpus.

View CDK16 target page →UniProt: Q00536 ↗

All 50 Compounds — Ranked by Evidence

Seliciclib

4.91

confidence

Alvocidib

4.52

confidence

Foretinib

4.34

confidence

Tozasertib

4.33

confidence

Ponatinib

4.26

confidence

Palbociclib

4.22

confidence

Bosutinib

4.08

confidence

Quizartinib

3.99

confidence

Dinaciclib

3.87

confidence

Silmitasertib

3.78

confidence

Pazopanib

3.69

confidence

Neratinib

3.66

confidence

Abemaciclib

3.66

confidence

Nintedanib

3.61

confidence

Rucaparib

3.58

confidence

Pelitinib

3.50

confidence

Bms 387032

3.47

confidence

Tae 684

3.43

confidence

Fedratinib

3.40

confidence

Linifanib

3.33

confidence

At 7519

3.33

confidence

Dabrafenib

3.30

confidence

Ribociclib

3.26

confidence

Tandutinib

3.22

confidence

Sp 600125

3.22

confidence

Dovitinib

3.09

confidence

Jnj 7706621

3.09

confidence

At 9283

3.09

confidence

Lestaurtinib

3.04

confidence

Pacritinib

3.04

confidence

Adavosertib

3.04

confidence

Pf 03758309

3.00

confidence

Ruboxistaurin

2.94

confidence

Defosbarasertib

2.89

confidence

Momelotinib

2.89

confidence

Milciclib

2.77

confidence

Pf 00562271

2.77

confidence

Pha 665752

2.71

confidence

Bms 345541

2.71

confidence

Kw 2449

2.64

confidence

Ast 487

2.56

confidence

Zotiraciclib

2.56

confidence

Su 014813

2.20

confidence

Rebastinib

2.20

confidence

Cyc 116

2.08

confidence

Enzastaurin

2.08

confidence

Rg 547

2.08

confidence

Uprosertib

1.95

confidence

Achyranthes Bidentata

1.00

confidence

Agastache Rugosa

1.00

confidence

The compounds above were identified through computational analysis of BindingDB binding assay data and PubMed literature for CDK16 (cyclin dependent kinase 16). Confidence scores reflect the strength and breadth of experimental evidence.

Explore related resources: CDK16 target overview · All biological targets · Biological pathways

Data from BindingDB and PubMed. For research purposes only. Not medical advice.