Compounds That Target CDK2

cyclin dependent kinase 2 · 201 compounds in BiohacksAI corpus

CDK2 (cyclin dependent kinase 2) is a protein kinase involved in intracellular signal transduction. Kinases phosphorylate downstream substrates to regulate cell growth, survival, and metabolism. The 201 compounds targeting CDK2 include both pharmaceutical inhibitors and natural compounds with evidence of kinase modulation, ranked by evidence strength from the BiohacksAI corpus.

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All 50 Compounds — Ranked by Evidence

Erlotinib

5.55

confidence

Seliciclib

4.91

confidence

Lapatinib

4.84

confidence

Alvocidib

4.52

confidence

Palbociclib

4.22

confidence

Ceritinib

4.19

confidence

Dinaciclib

3.87

confidence

Silmitasertib

3.78

confidence

Olomoucine

3.71

confidence

Abemaciclib

3.66

confidence

Nintedanib

3.61

confidence

Wogonin

3.61

confidence

Bms 387032

3.47

confidence

Tae 684

3.43

confidence

Saracatinib

3.33

confidence

At 7519

3.33

confidence

Dabrafenib

3.30

confidence

Ribociclib

3.26

confidence

Sp 600125

3.22

confidence

Purvalanola

3.18

confidence

Pyrogallol

3.14

confidence

Jnj 7706621

3.09

confidence

Lestaurtinib

3.04

confidence

Danusertib

2.94

confidence

Salirasib

2.94

confidence

Momelotinib

2.89

confidence

K 252a

2.83

confidence

Su 9516

2.83

confidence

Milciclib

2.77

confidence

Pf 00562271

2.77

confidence

6 Benzylaminopurine

2.77

confidence

Pha 665752

2.71

confidence

Crenolanib

2.71

confidence

Azd 5438

2.71

confidence

Closantel

2.71

confidence

Ast 487

2.56

confidence

Zotiraciclib

2.56

confidence

Atuveciclib

2.56

confidence

Roniciclib

2.56

confidence

Indazole

2.56

confidence

Defactinib

2.48

confidence

5 Nitro 2 Phenylpropylaminobenzoic Acid Nppb

2.40

confidence

Rebastinib

2.20

confidence

Ct 7001

2.20

confidence

Acid Blue 25

2.20

confidence

Cyc 116

2.08

confidence

Enzastaurin

2.08

confidence

Rg 547

2.08

confidence

Gsk 269962a

2.08

confidence

Purvalanol B

2.08

confidence

The compounds above were identified through computational analysis of BindingDB binding assay data and PubMed literature for CDK2 (cyclin dependent kinase 2). Confidence scores reflect the strength and breadth of experimental evidence.

Explore related resources: CDK2 target overview · All biological targets · Biological pathways

Data from BindingDB and PubMed. For research purposes only. Not medical advice.