Compounds That Target CDK7

cyclin dependent kinase 7 · 122 compounds in BiohacksAI corpus

CDK7 (cyclin dependent kinase 7) is a protein kinase involved in intracellular signal transduction. Kinases phosphorylate downstream substrates to regulate cell growth, survival, and metabolism. The 122 compounds targeting CDK7 include both pharmaceutical inhibitors and natural compounds with evidence of kinase modulation, ranked by evidence strength from the BiohacksAI corpus.

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Most Studied Compounds for CDK7

Ha1077

11+

studies

All 50 Compounds — Ranked by Evidence

Gefitinib

5.67

confidence

Seliciclib

4.91

confidence

Alvocidib

4.52

confidence

Foretinib

4.34

confidence

Vandetanib

4.30

confidence

Ruxolitinib

4.23

confidence

Pi 103

4.17

confidence

Bosutinib

4.08

confidence

Doramapimod

4.06

confidence

Bi 2536

4.01

confidence

Quizartinib

3.99

confidence

Dinaciclib

3.87

confidence

Silmitasertib

3.78

confidence

Neratinib

3.66

confidence

Abemaciclib

3.66

confidence

Nintedanib

3.61

confidence

Bms 387032

3.47

confidence

Tae 684

3.43

confidence

Fedratinib

3.40

confidence

Linifanib

3.33

confidence

At 7519

3.33

confidence

Tandutinib

3.22

confidence

Dovitinib

3.09

confidence

Jnj 7706621

3.09

confidence

Lestaurtinib

3.04

confidence

Pf 03758309

3.00

confidence

Ruboxistaurin

2.94

confidence

Danusertib

2.94

confidence

Defosbarasertib

2.89

confidence

R 406

2.83

confidence

Milciclib

2.77

confidence

Pf 00562271

2.77

confidence

Pha 665752

2.71

confidence

Bms 345541

2.71

confidence

Azd 5438

2.71

confidence

Kw 2449

2.64

confidence

Ast 487

2.56

confidence

Zotiraciclib

2.56

confidence

Roniciclib

2.56

confidence

Defactinib

2.48

confidence

Gsk 461364

2.40

confidence

Su 014813

2.20

confidence

Ct 7001

2.20

confidence

Enzastaurin

2.08

confidence

Rg 547

2.08

confidence

Zemirciclib

2.08

confidence

Uprosertib

1.95

confidence

S Roscovitine

1.95

confidence

Cyc 065

1.95

confidence

Ha1077

11+

studies

1.10

confidence

The compounds above were identified through computational analysis of BindingDB binding assay data and PubMed literature for CDK7 (cyclin dependent kinase 7). Confidence scores reflect the strength and breadth of experimental evidence.

Explore related resources: CDK7 target overview · All biological targets · Biological pathways

Data from BindingDB and PubMed. For research purposes only. Not medical advice.