Compounds That Target CDK9

cyclin dependent kinase 9 · 45 compounds in BiohacksAI corpus

CDK9 (cyclin dependent kinase 9) is a protein kinase involved in intracellular signal transduction. Kinases phosphorylate downstream substrates to regulate cell growth, survival, and metabolism. The 45 compounds targeting CDK9 include both pharmaceutical inhibitors and natural compounds with evidence of kinase modulation, ranked by evidence strength from the BiohacksAI corpus.

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Most Studied Compounds for CDK9

Alsterpaullone

12+

studies

All 45 Compounds — Ranked by Evidence

Seliciclib

4.91

confidence

Alvocidib

4.52

confidence

Foretinib

4.34

confidence

Palbociclib

4.22

confidence

Dinaciclib

3.87

confidence

Molibresib

3.81

confidence

Abemaciclib

3.66

confidence

Fasudil

3.66

confidence

Wogonin

3.61

confidence

Bms 387032

3.47

confidence

Fedratinib

3.40

confidence

Linifanib

3.33

confidence

At 7519

3.33

confidence

Ribociclib

3.26

confidence

Sulfuretin

3.14

confidence

Jnj 7706621

3.09

confidence

At 9283

3.09

confidence

Lestaurtinib

3.04

confidence

Pacritinib

3.04

confidence

Momelotinib

2.89

confidence

Pf 00562271

2.77

confidence

Pha 665752

2.71

confidence

Crenolanib

2.71

confidence

Bms 345541

2.71

confidence

Azd 5438

2.71

confidence

Ast 487

2.56

confidence

Zotiraciclib

2.56

confidence

Atuveciclib

2.56

confidence

Roniciclib

2.56

confidence

Defactinib

2.48

confidence

Ripasudil

2.40

confidence

Decernotinib

2.20

confidence

Y 39983

2.20

confidence

Ct 7001

2.20

confidence

Cyc 116

2.08

confidence

Enzastaurin

2.08

confidence

Rg 547

2.08

confidence

Zemirciclib

2.08

confidence

Istisociclib

2.08

confidence

Sel 120 Free Base

1.95

confidence

S Roscovitine

1.95

confidence

Cyc 065

1.95

confidence

Meriolin 1

1.95

confidence

Voruciclib

1.79

confidence

Alsterpaullone

12+

studies

0.69

confidence

The compounds above were identified through computational analysis of BindingDB binding assay data and PubMed literature for CDK9 (cyclin dependent kinase 9). Confidence scores reflect the strength and breadth of experimental evidence.

Explore related resources: CDK9 target overview · All biological targets · Biological pathways

Data from BindingDB and PubMed. For research purposes only. Not medical advice.