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Compounds That Target CDK9

cyclin dependent kinase 9 · 146 compounds in BiohacksAI corpus

CDK9 (cyclin dependent kinase 9) is a protein kinase involved in intracellular signal transduction. Kinases phosphorylate downstream substrates to regulate cell growth, survival, and metabolism. The 146 compounds targeting CDK9 include both pharmaceutical inhibitors and natural compounds with evidence of kinase modulation, ranked by evidence strength from the BiohacksAI corpus.

Most Studied Compounds for CDK9
500+
studies
499+
studies
12+
studies
All 51 Compounds — Ranked by Evidence
1
Seliciclib
4.91
confidence
2
Alvocidib
4.52
confidence
3
Foretinib
4.34
confidence
4
Palbociclib
4.22
confidence
5
Dinaciclib
3.87
confidence
6
Molibresib
3.81
confidence
7
Fasudil
3.66
confidence
8
Abemaciclib
3.66
confidence
9
Wogonin
3.61
confidence
10
Bms 387032
3.47
confidence
11
Fedratinib
3.40
confidence
12
Linifanib
3.33
confidence
13
At 7519
3.33
confidence
14
Ribociclib
3.26
confidence
15
Sulfuretin
3.14
confidence
16
Jnj 7706621
3.09
confidence
17
At 9283
3.09
confidence
18
Lestaurtinib
3.04
confidence
19
Pacritinib
3.04
confidence
20
Momelotinib
2.89
confidence
21
Pf 00562271
2.77
confidence
22
Azd 5438
2.71
confidence
23
Pha 665752
2.71
confidence
24
Crenolanib
2.71
confidence
25
Bms 345541
2.71
confidence
26
Ast 487
2.56
confidence
27
Zotiraciclib
2.56
confidence
28
Atuveciclib
2.56
confidence
29
Roniciclib
2.56
confidence
30
Defactinib
2.48
confidence
31
Ripasudil
2.40
confidence
32
Y 39983
2.20
confidence
33
Decernotinib
2.20
confidence
34
Ct 7001
2.20
confidence
35
Zemirciclib
2.08
confidence
36
Cyc 116
2.08
confidence
37
Enzastaurin
2.08
confidence
38
Rg 547
2.08
confidence
39
Istisociclib
2.08
confidence
40
Meriolin 1
1.95
confidence
41
Sel 120 Free Base
1.95
confidence
42
S Roscovitine
1.95
confidence
43
Cyc 065
1.95
confidence
44
Voruciclib
1.79
confidence
45
Chaenomeles Speciosa
1.00
confidence
500+
studies
1.00
confidence
47
Aloe Vera
1.00
confidence
48
Arctium Lappa
1.00
confidence
49
Artemisia Argyi
1.00
confidence
499+
studies
1.00
confidence
12+
studies
0.69
confidence

The compounds above were identified through computational analysis of BindingDB binding assay data and PubMed literature for CDK9 (cyclin dependent kinase 9). Confidence scores reflect the strength and breadth of experimental evidence.

Explore related resources: CDK9 target overview · All biological targets · Biological pathways

Data from BindingDB and PubMed. For research purposes only. Not medical advice.