Compounds That Target CDKL2

cyclin dependent kinase like 2 · 20 compounds in BiohacksAI corpus

CDKL2 (cyclin dependent kinase like 2) is a protein kinase involved in intracellular signal transduction. Kinases phosphorylate downstream substrates to regulate cell growth, survival, and metabolism. The 20 compounds targeting CDKL2 include both pharmaceutical inhibitors and natural compounds with evidence of kinase modulation, ranked by evidence strength from the BiohacksAI corpus.

View CDKL2 target page →UniProt: Q92772 ↗

Most Studied Compounds for CDKL2

Sorafenib

300+

studies

Axitinib

298+

studies

Crizotinib

298+

studies

All 20 Compounds — Ranked by Evidence

Foretinib

4.34

confidence

Tozasertib

4.33

confidence

Quizartinib

3.99

confidence

Nintedanib

3.61

confidence

Bms 387032

3.47

confidence

Fedratinib

3.40

confidence

At 7519

3.33

confidence

Tandutinib

3.22

confidence

Dovitinib

3.09

confidence

Lestaurtinib

3.04

confidence

Defosbarasertib

2.89

confidence

R 406

2.83

confidence

Pha 665752

2.71

confidence

Kw 2449

2.64

confidence

Ast 487

2.56

confidence

Su 014813

2.20

confidence

Enzastaurin

2.08

confidence

Sorafenib

300+

studies

1.10

confidence

Axitinib

298+

studies

0.69

confidence

Crizotinib

298+

studies

0.69

confidence

The compounds above were identified through computational analysis of BindingDB binding assay data and PubMed literature for CDKL2 (cyclin dependent kinase like 2). Confidence scores reflect the strength and breadth of experimental evidence.

Explore related resources: CDKL2 target overview · All biological targets · Biological pathways

Data from BindingDB and PubMed. For research purposes only. Not medical advice.