Compounds That Target CHRM1

cholinergic receptor muscarinic 1 · 317 compounds in BiohacksAI corpus

CHRM1 (cholinergic receptor muscarinic 1) is a receptor that mediates ligand-dependent signaling relevant to physiology, behavior, and metabolism. The 317 compounds with documented CHRM1 interactions span synthetic agonists, antagonists, and natural ligands identified through BindingDB binding assays and PubMed literature in the BiohacksAI corpus.

View CHRM1 target page →UniProt: P11229 ↗

Most Studied Compounds for CHRM1

Quetiapine

994+

studies

Arecoline

299+

studies

Ivermectin

298+

studies

Scopolamine

298+

studies

Atropine

296+

studies

All 50 Compounds — Ranked by Evidence

Tamoxifen

5.88

confidence

Clozapine

5.81

confidence

Sb 203580

4.92

confidence

Risperidone

4.89

confidence

Quinacrine

4.63

confidence

Berberine Chloride

4.56

confidence

Terfenadine

4.55

confidence

Thioridazine

4.52

confidence

Amiodarone

4.51

confidence

Carbachol

4.49

confidence

Olanzapine

4.44

confidence

Atropine

296+

studies

4.41

confidence

Paroxetine

4.39

confidence

Acetylcholine

4.29

confidence

Clomipramine

4.28

confidence

Diphenhydramine

4.22

confidence

Plerixafor

4.20

confidence

Promazine

4.19

confidence

Ivermectin

298+

studies

4.11

confidence

Pirenzepine

4.11

confidence

Arecoline

299+

studies

4.06

confidence

Diethylstilbestrol

4.06

confidence

Gentian Violet

4.03

confidence

Ziprasidone

3.99

confidence

Fluphenazine

3.91

confidence

Pilocarpinedrugage

3.69

confidence

Oxotremorine

3.61

confidence

Doxepin

3.50

confidence

Ketotifen

3.47

confidence

Hydroxychloroquine

3.47

confidence

Perhexiline

3.37

confidence

Prochlorperazine

3.33

confidence

Desloratadine

3.26

confidence

Azelastine

3.26

confidence

Tolterodine

3.26

confidence

Oxybutynin

3.22

confidence

Methoctramine

3.18

confidence

Xanomeline

3.18

confidence

Linagliptin

3.18

confidence

4 Damp

3.14

confidence

N Methylscopolamineheterocyclic

3.00

confidence

Orphenadrine

2.94

confidence

Darifenacin

2.89

confidence

Scopolamine

298+

studies

2.83

confidence

N Desmethylclozapine

2.77

confidence

Difluorobenztropine

2.77

confidence

Methscopolamine

2.71

confidence

Ebastine

2.64

confidence

Carbetapentane

2.64

confidence

Quetiapine

994+

studies

2.56

confidence

The compounds above were identified through computational analysis of BindingDB binding assay data and PubMed literature for CHRM1 (cholinergic receptor muscarinic 1). Confidence scores reflect the strength and breadth of experimental evidence.

Explore related resources: CHRM1 target overview · All biological targets · Biological pathways

Data from BindingDB and PubMed. For research purposes only. Not medical advice.