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Compounds That Target CYP19A1

cytochrome P450 family 19 subfamily A member 1 · 252 compounds in BiohacksAI corpus

CYP19A1 (cytochrome P450 family 19 subfamily A member 1) is a cytochrome P450 enzyme involved in the metabolism of drugs, hormones, and dietary compounds. CYP enzymes are critical determinants of pharmacokinetics and drug-herb interactions. The 252 compounds listed here have documented interactions with CYP19A1 based on BindingDB inhibition and binding assay data, making this resource valuable for assessing compound safety and interaction profiles.

Most Studied Compounds for CYP19A1
300+
studies
300+
studies
300+
studies
300+
studies
300+
studies
300+
studies
299+
studies
298+
studies
298+
studies
200+
studies
All 50 Compounds — Ranked by Evidence
1
Alpha Naphthoflavone
4.67
confidence
2
Stanolone
4.55
confidence
3
Isoliquiritigenin
4.50
confidence
4
Flavone
4.34
confidence
5
Galangin
4.30
confidence
6
Ns 398
4.28
confidence
7
Mangostin
4.14
confidence
8
Biochanin
4.14
confidence
9
Aminoglutethimide
4.11
confidence
10
Nimesulide
4.04
confidence
11
7 Hydroxyflavone
4.01
confidence
298+
studies
3.99
confidence
13
Pinocembrin
3.78
confidence
300+
studies
3.74
confidence
15
Phloretin
3.71
confidence
16
Liquirtigenin
3.61
confidence
17
Trismethoxyresveratrol
3.56
confidence
18
Doconexent
3.56
confidence
19
Flavanone
3.47
confidence
20
Linolenic Acid
3.33
confidence
21
Irosustat
3.30
confidence
22
78 Dihydroxyflavone
3.14
confidence
23
4 Hydroxychalcone
3.09
confidence
298+
studies
3.00
confidence
25
Benzylimidazole
2.89
confidence
26
Osilodrostat
2.89
confidence
27
Icosapent
2.83
confidence
28
Gossypetin
2.83
confidence
29
Liarozole
2.71
confidence
30
Endoxifen
2.71
confidence
31
Dexfadrostat
2.48
confidence
32
7 Methoxyflavone
2.48
confidence
33
Naringeninflavonoids
2.30
confidence
34
Tyrphostin 23
2.30
confidence
35
Abyssinone Ii
2.30
confidence
36
Chrysinflavonoids
2.20
confidence
300+
studies
2.20
confidence
38
Azalanstat
2.20
confidence
39
Morachalcone A
2.20
confidence
40
E 4 Styrylaniline
1.95
confidence
41
Garcinone D
1.95
confidence
300+
studies
1.79
confidence
43
Clotrimazoleheterocyclic
1.79
confidence
44
S Fadrozole
1.79
confidence
45
Garcinone E
1.79
confidence
200+
studies
1.61
confidence
299+
studies
1.61
confidence
300+
studies
1.61
confidence
300+
studies
1.61
confidence
300+
studies
1.61
confidence

The compounds above were identified through computational analysis of BindingDB binding assay data and PubMed literature for CYP19A1 (cytochrome P450 family 19 subfamily A member 1). Confidence scores reflect the strength and breadth of experimental evidence.

Explore related resources: CYP19A1 target overview · All biological targets · Biological pathways

Data from BindingDB and PubMed. For research purposes only. Not medical advice.