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BiohacksAI/Targets/CYP46A1/Compounds

Compounds That Target CYP46A1

cytochrome P450 family 46 subfamily A member 1 · 118 compounds in BiohacksAI corpus

CYP46A1 (cytochrome P450 family 46 subfamily A member 1) is a cytochrome P450 enzyme involved in the metabolism of drugs, hormones, and dietary compounds. CYP enzymes are critical determinants of pharmacokinetics and drug-herb interactions. The 118 compounds listed here have documented interactions with CYP46A1 based on BindingDB inhibition and binding assay data, making this resource valuable for assessing compound safety and interaction profiles.

View CYP46A1 target page →UniProt: Q9Y6A2 ↗
Most Studied Compounds for CYP46A1
1
Allium Sativum
500+
studies
2
Curcuma Longa
500+
studies
3
Portulaca Oleracea
500+
studies
4
Centella Asiatica
499+
studies
5
Panax Ginseng
300+
studies
6
Cholesterol
300+
studies
7
Voriconazole
299+
studies
8
Ginkgo Biloba
299+
studies
All 51 Compounds — Ranked by Evidence
1
Efavirenz
5.81
confidence
2
Thioperamide
4.25
confidence
3
Voriconazole
299+
studies
1.79
confidence
4
Allium Sativum
500+
studies
1.00
confidence
5
Aloe Vera
1.00
confidence
6
Arctium Lappa
1.00
confidence
7
Artemisia Capillaris
1.00
confidence
8
Aster Tataricus
1.00
confidence
9
Atractylodes Macrocephala
1.00
confidence
10
Bombyx Mori
1.00
confidence
11
Centella Asiatica
499+
studies
1.00
confidence
12
Chaenomeles Speciosa
1.00
confidence
13
Citrus Reticulata
1.00
confidence
14
Cnidium Monnieri
1.00
confidence
15
Commiphora Myrrha
1.00
confidence
16
Crataegus Pinnatifida
1.00
confidence
17
Curcuma Longa
500+
studies
1.00
confidence
18
Cynomorium Songaricum
1.00
confidence
19
Ephedra Sinica
1.00
confidence
20
Eriobotrya Japonica
1.00
confidence
21
Eucommia Ulmoides
1.00
confidence
22
Forsythia Suspensa
1.00
confidence
23
Fritillaria Cirrhosa
1.00
confidence
24
Gentiana Macrophylla
1.00
confidence
25
Ginkgo Biloba
299+
studies
1.00
confidence
26
Glycine Max
1.00
confidence
27
Glycyrrhiza Uralensis
1.00
confidence
28
Inula Japonica
1.00
confidence
29
Ligusticum Chuanxiong
1.00
confidence
30
Lilium Lancifolium
1.00
confidence
31
Litchi Chinensis
1.00
confidence
32
Lithospermum Erythrorhizon
1.00
confidence
33
Lobelia Chinensis
1.00
confidence
34
Lonicera Japonica
1.00
confidence
35
Morus Alba
1.00
confidence
36
Nelumbo Nucifera
1.00
confidence
37
Paeonia Lactiflora
1.00
confidence
38
Panax Ginseng
300+
studies
1.00
confidence
39
Panax Notoginseng
1.00
confidence
40
Perilla Frutescens
1.00
confidence
41
Peucedanum Praeruptorum
1.00
confidence
42
Pinellia Ternata
1.00
confidence
43
Piper Nigrum
1.00
confidence
44
Polygonum Cuspidatum
1.00
confidence
45
Poria Cocos
1.00
confidence
46
Portulaca Oleracea
500+
studies
1.00
confidence
47
Prunella Vulgaris
1.00
confidence
48
Prunus Armeniaca
1.00
confidence
49
Achyranthes Bidentata
1.00
confidence
50
Agastache Rugosa
1.00
confidence
51
Cholesterol
300+
studies
0.69
confidence

The compounds above were identified through computational analysis of BindingDB binding assay data and PubMed literature for CYP46A1 (cytochrome P450 family 46 subfamily A member 1). Confidence scores reflect the strength and breadth of experimental evidence.

Explore related resources: CYP46A1 target overview · All biological targets · Biological pathways

Data from BindingDB and PubMed. For research purposes only. Not medical advice.