Compounds That Target DRD1

dopamine receptor D1 · 209 compounds in BiohacksAI corpus

DRD1 (dopamine receptor D1) is a receptor that mediates ligand-dependent signaling relevant to physiology, behavior, and metabolism. The 209 compounds with documented DRD1 interactions span synthetic agonists, antagonists, and natural ligands identified through BindingDB binding assays and PubMed literature in the BiohacksAI corpus.

View DRD1 target page →UniProt: P21728 ↗

Most Studied Compounds for DRD1

Pergolide

299+

studies

Ivermectin

298+

studies

Aripiprazole

298+

studies

All 50 Compounds — Ranked by Evidence

Tamoxifen

5.88

confidence

Clozapine

5.81

confidence

Serotonin

5.47

confidence

Dopamine

5.45

confidence

Risperidone

4.89

confidence

Raloxifene

4.77

confidence

Terfenadine

4.55

confidence

Thioridazine

4.52

confidence

Amiodarone

4.51

confidence

Nelfinavir

4.51

confidence

Isoliquiritigenin

4.50

confidence

Olanzapine

4.44

confidence

Quinpirole

4.42

confidence

Clomipramine

4.28

confidence

Spiperone

4.23

confidence

Promazine

4.19

confidence

Pimozide

4.19

confidence

Ivermectin

298+

studies

4.11

confidence

Sch 23390

4.08

confidence

Diethylstilbestrol

4.06

confidence

Gentian Violet

4.03

confidence

Ziprasidone

3.99

confidence

Fluphenazine

3.91

confidence

Ciglitazone

3.81

confidence

Ritanserin

3.61

confidence

Sertindole

3.58

confidence

Doxepin

3.50

confidence

L 365260

3.50

confidence

Ketotifen

3.47

confidence

Prochlorperazine

3.33

confidence

Droperidol

3.30

confidence

Ropinirole

3.26

confidence

Bp 897

3.18

confidence

Dihydrexidine

3.14

confidence

R Skf 38393

3.04

confidence

Skf 38393

3.04

confidence

Chlorprothixene

3.00

confidence

R N Propylnorapomorphine

3.00

confidence

Pptn

2.89

confidence

Cariprazine

2.83

confidence

Aripiprazole

298+

studies

2.77

confidence

Psilocin

2.77

confidence

Tetrahydropalmatine

2.77

confidence

Paliperidone

2.71

confidence

Volinanserin

2.71

confidence

Fenoldopam

2.71

confidence

Pergolide

299+

studies

2.64

confidence

Ebastine

2.64

confidence

Fauc 113

2.64

confidence

Canadine

2.64

confidence

The compounds above were identified through computational analysis of BindingDB binding assay data and PubMed literature for DRD1 (dopamine receptor D1). Confidence scores reflect the strength and breadth of experimental evidence.

Explore related resources: DRD1 target overview · All biological targets · Biological pathways

Data from BindingDB and PubMed. For research purposes only. Not medical advice.