Compounds That Target DRD2

dopamine receptor D2 · 392 compounds in BiohacksAI corpus

DRD2 (dopamine receptor D2) is a receptor that mediates ligand-dependent signaling relevant to physiology, behavior, and metabolism. The 392 compounds with documented DRD2 interactions span synthetic agonists, antagonists, and natural ligands identified through BindingDB binding assays and PubMed literature in the BiohacksAI corpus.

View DRD2 target page →UniProt: P14416 ↗

Most Studied Compounds for DRD2

Raclopride

300+

studies

Buspirone

299+

studies

Domperidone

299+

studies

Pergolide

299+

studies

Metoclopramide

297+

studies

Pramipexole

297+

studies

All 50 Compounds — Ranked by Evidence

Tamoxifen

5.88

confidence

Clozapine

5.81

confidence

Imipramine

5.69

confidence

Dopamine

5.45

confidence

8 Oh Dpat

4.98

confidence

Risperidone

4.89

confidence

Ketanserin

4.85

confidence

Raloxifene

4.77

confidence

Terfenadine

4.55

confidence

Thioridazine

4.52

confidence

Amiodarone

4.51

confidence

Olanzapine

4.44

confidence

Quinpirole

4.42

confidence

Clomipramine

4.28

confidence

Spiperone

4.23

confidence

Promazine

4.19

confidence

Pimozide

4.19

confidence

Sch 23390

4.08

confidence

Diethylstilbestrol

4.06

confidence

Gentian Violet

4.03

confidence

Ziprasidone

3.99

confidence

Loperamide

3.93

confidence

Fluphenazine

3.91

confidence

Salmeterol

3.76

confidence

Ritanserin

3.61

confidence

Lysergide

3.61

confidence

Sertindole

3.58

confidence

Raclopride

300+

studies

3.40

confidence

Prochlorperazine

3.33

confidence

Droperidol

3.30

confidence

Buspirone

299+

studies

3.26

confidence

Ropinirole

3.26

confidence

L 745870

3.22

confidence

Bmy 7378

3.22

confidence

Bp 897

3.18

confidence

Formoterol

3.18

confidence

Intepirdine

3.14

confidence

Dihydrexidine

3.14

confidence

Ipsapirone

3.04

confidence

R Skf 38393

3.04

confidence

Preclamol

3.04

confidence

Chlorprothixene

3.00

confidence

R N Propylnorapomorphine

3.00

confidence

Domperidone

299+

studies

2.94

confidence

Eticlopride

2.94

confidence

Metoclopramide

297+

studies

2.89

confidence

Darifenacin

2.89

confidence

5 Oh Dpat

2.89

confidence

Pergolide

299+

studies

2.83

confidence

Pramipexole

297+

studies

2.83

confidence

The compounds above were identified through computational analysis of BindingDB binding assay data and PubMed literature for DRD2 (dopamine receptor D2). Confidence scores reflect the strength and breadth of experimental evidence.

Explore related resources: DRD2 target overview · All biological targets · Biological pathways

Data from BindingDB and PubMed. For research purposes only. Not medical advice.