Compounds That Target DRD3

dopamine receptor D3 · 407 compounds in BiohacksAI corpus

DRD3 (dopamine receptor D3) is a receptor that mediates ligand-dependent signaling relevant to physiology, behavior, and metabolism. The 407 compounds with documented DRD3 interactions span synthetic agonists, antagonists, and natural ligands identified through BindingDB binding assays and PubMed literature in the BiohacksAI corpus.

View DRD3 target page →UniProt: P35462 ↗

Most Studied Compounds for DRD3

Ivermectin

298+

studies

Aripiprazole

298+

studies

Pramipexole

297+

studies

All 50 Compounds — Ranked by Evidence

Tamoxifen

5.88

confidence

Clozapine

5.81

confidence

Serotonin

5.47

confidence

Dopamine

5.45

confidence

8 Oh Dpat

4.98

confidence

Saquinavir

4.98

confidence

Risperidone

4.89

confidence

Raloxifene

4.77

confidence

Quinacrine

4.63

confidence

Terfenadine

4.55

confidence

Thioridazine

4.52

confidence

Amiodarone

4.51

confidence

Isoliquiritigenin

4.50

confidence

Olanzapine

4.44

confidence

Quinpirole

4.42

confidence

Clomipramine

4.28

confidence

Spiperone

4.23

confidence

Promazine

4.19

confidence

Pimozide

4.19

confidence

Ivermectin

298+

studies

4.11

confidence

Diethylstilbestrol

4.06

confidence

Gentian Violet

4.03

confidence

Ziprasidone

3.99

confidence

Loperamide

3.93

confidence

Fluphenazine

3.91

confidence

Ciglitazone

3.81

confidence

Salmeterol

3.76

confidence

Amentoflavone

3.76

confidence

Pramipexole

297+

studies

3.71

confidence

Ritanserin

3.61

confidence

Lysergide

3.61

confidence

Sertindole

3.58

confidence

Aripiprazole

298+

studies

3.50

confidence

Doxepin

3.50

confidence

Ketotifen

3.47

confidence

Mirtazapine

3.43

confidence

Methadone

3.40

confidence

Dobutamine

3.37

confidence

Prochlorperazine

3.33

confidence

Droperidol

3.30

confidence

Desloratadine

3.26

confidence

Ropinirole

3.26

confidence

L 745870

3.22

confidence

Oxybutynin

3.22

confidence

Rabeprazole

3.18

confidence

Bp 897

3.18

confidence

Formoterol

3.18

confidence

Ipsapirone

3.04

confidence

Preclamol

3.04

confidence

Chlorprothixene

3.00

confidence

The compounds above were identified through computational analysis of BindingDB binding assay data and PubMed literature for DRD3 (dopamine receptor D3). Confidence scores reflect the strength and breadth of experimental evidence.

Explore related resources: DRD3 target overview · All biological targets · Biological pathways

Data from BindingDB and PubMed. For research purposes only. Not medical advice.