Compounds That Target DRD4

dopamine receptor D4 · 232 compounds in BiohacksAI corpus

DRD4 (dopamine receptor D4) is a receptor that mediates ligand-dependent signaling relevant to physiology, behavior, and metabolism. The 232 compounds with documented DRD4 interactions span synthetic agonists, antagonists, and natural ligands identified through BindingDB binding assays and PubMed literature in the BiohacksAI corpus.

View DRD4 target page →UniProt: P21917 ↗

Most Studied Compounds for DRD4

Aripiprazole

298+

studies

Pramipexole

297+

studies

All 50 Compounds — Ranked by Evidence

Tamoxifen

5.88

confidence

Clozapine

5.81

confidence

Dopamine

5.45

confidence

Prazosin

5.15

confidence

Risperidone

4.89

confidence

Ketanserin

4.85

confidence

Thioridazine

4.52

confidence

Amiodarone

4.51

confidence

Olanzapine

4.44

confidence

Quinpirole

4.42

confidence

Spiperone

4.23

confidence

Ziprasidone

3.99

confidence

Loperamide

3.93

confidence

Fluphenazine

3.91

confidence

Salmeterol

3.76

confidence

Ritanserin

3.61

confidence

Lysergide

3.61

confidence

Sertindole

3.58

confidence

Way 100635

3.53

confidence

Methadone

3.40

confidence

Prochlorperazine

3.33

confidence

Ropinirole

3.26

confidence

L 745870

3.22

confidence

Purvalanola

3.18

confidence

Bp 897

3.18

confidence

Ipsapirone

3.04

confidence

Preclamol

3.04

confidence

Aripiprazole

298+

studies

3.00

confidence

Eticlopride

2.94

confidence

Cariprazine

2.83

confidence

Paliperidone

2.71

confidence

Ebastine

2.64

confidence

Fauc 113

2.64

confidence

Clebopride

2.64

confidence

Canadine

2.64

confidence

Pramipexole

297+

studies

2.56

confidence

Stepholidine

2.56

confidence

Bay 293

2.48

confidence

Auranofin

2.48

confidence

Dopamine Hydrochloride

2.48

confidence

Penfluridol

2.40

confidence

Pd 168077

2.40

confidence

Isoclozapine

2.40

confidence

Loperamide Hydrochloride

2.30

confidence

Ecopipam

2.30

confidence

Silodosin

2.20

confidence

Nemonapride

2.20

confidence

Gsk778

2.08

confidence

Nantenine

2.08

confidence

Fananserin

2.08

confidence

The compounds above were identified through computational analysis of BindingDB binding assay data and PubMed literature for DRD4 (dopamine receptor D4). Confidence scores reflect the strength and breadth of experimental evidence.

Explore related resources: DRD4 target overview · All biological targets · Biological pathways

Data from BindingDB and PubMed. For research purposes only. Not medical advice.