Compounds That Target DYRK1A

dual specificity tyrosine phosphorylation regulated kinase 1A · 94 compounds in BiohacksAI corpus

DYRK1A (dual specificity tyrosine phosphorylation regulated kinase 1A) is a biological target with 94 documented compound interactions in the BiohacksAI corpus. The compounds listed below have been identified through computational analysis of BindingDB binding assay data and PubMed literature. Each interaction is ranked by confidence score reflecting the breadth and strength of experimental evidence. This resource supports research into DYRK1A modulation for therapeutic and biohacking applications.

View DYRK1A target page →UniProt: Q63470 ↗

Most Studied Compounds for DYRK1A

Harmine

300+

studies

Kaempferol

300+

studies

All 50 Compounds — Ranked by Evidence

Epigalocatechin Gallate

5.40

confidence

Seliciclib

4.91

confidence

Alvocidib

4.52

confidence

Ruxolitinib

4.23

confidence

Epicatechin Gallate

3.95

confidence

Midostaurin

3.85

confidence

Silmitasertib

3.78

confidence

Abemaciclib

3.66

confidence

Rucaparib

3.58

confidence

Canertinib

3.53

confidence

6bio

3.50

confidence

Bms 387032

3.47

confidence

Tae 684

3.43

confidence

At 7519

3.33

confidence

Niraparib

3.30

confidence

Iodotubercidin

3.30

confidence

Purvalanola

3.18

confidence

Tetrabromobenzotriazole

3.14

confidence

At 9283

3.09

confidence

Gallocatechin Gallate

3.09

confidence

Lestaurtinib

3.04

confidence

Ruboxistaurin

2.94

confidence

Barasertib

2.89

confidence

R 406

2.83

confidence

K 252a

2.83

confidence

Catechingallate

2.77

confidence

Milciclib

2.77

confidence

Quinalizarin

2.77

confidence

Crenolanib

2.71

confidence

Kw 2449

2.64

confidence

Zotiraciclib

2.56

confidence

Defactinib

2.48

confidence

Sgx 523

2.30

confidence

Azd 7762

2.30

confidence

Su 014813

2.20

confidence

Leucettamine B

2.20

confidence

Bgt 226 Free Base

2.20

confidence

Enzastaurin

2.08

confidence

Cyc 116

2.08

confidence

Licocoumarone

2.08

confidence

Rg 547

2.08

confidence

Tg100 115

2.08

confidence

Demethylbellidifolin

1.95

confidence

Gsk 1059615

1.95

confidence

Harmine

300+

studies

1.95

confidence

Sel 120 Free Base

1.95

confidence

Uprosertib

1.95

confidence

Lorecivivint

1.79

confidence

T3 Clk

1.79

confidence

Kaempferol

300+

studies

1.10

confidence

The compounds above were identified through computational analysis of BindingDB binding assay data and PubMed literature for DYRK1A (dual specificity tyrosine phosphorylation regulated kinase 1A). Confidence scores reflect the strength and breadth of experimental evidence.

Explore related resources: DYRK1A target overview · All biological targets · Biological pathways

Data from BindingDB and PubMed. For research purposes only. Not medical advice.