BETABiohacksAI is a research tool for informational purposes only. All outputs are computational hypothesis candidates — not confirmed mechanisms, not medical advice, and not a substitute for professional medical judgment. Independent experimental validation is always required.
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Compounds That Target ERBB4

erb-b2 receptor tyrosine kinase 4 · 142 compounds in BiohacksAI corpus

ERBB4 (erb-b2 receptor tyrosine kinase 4) is a biological target with 142 documented compound interactions in the BiohacksAI corpus. The compounds listed below have been identified through computational analysis of BindingDB binding assay data and PubMed literature. Each interaction is ranked by confidence score reflecting the breadth and strength of experimental evidence. This resource supports research into ERBB4 modulation for therapeutic and biohacking applications.

Most Studied Compounds for ERBB4
299+
studies
297+
studies
117+
studies
All 36 Compounds — Ranked by Evidence
1
Gefitinib
5.67
confidence
2
Erlotinib
5.55
confidence
3
Sb 203580
4.92
confidence
4
Ibrutinib
4.86
confidence
5
Lapatinib
4.84
confidence
6
Alvocidib
4.52
confidence
7
Foretinib
4.34
confidence
8
Vandetanib
4.30
confidence
9
Bosutinib
4.08
confidence
10
Bi 2536
4.01
confidence
11
Midostaurin
3.85
confidence
12
Brigatinib
3.81
confidence
13
Neratinib
3.66
confidence
14
Canertinib
3.53
confidence
15
Pelitinib
3.50
confidence
16
Tae 684
3.43
confidence
17
Fedratinib
3.40
confidence
18
Acalabrutinib
3.22
confidence
19
Dacomitinib Anhydrous
3.14
confidence
20
Lestaurtinib
3.04
confidence
21
Defosbarasertib
2.89
confidence
22
R 406
2.83
confidence
23
Cediranib
2.83
confidence
24
Ritlecitinib
2.77
confidence
25
Zanubrutinib
2.56
confidence
26
Evobrutinib
2.48
confidence
27
Tak 285
2.40
confidence
28
Tg100 115
2.08
confidence
29
Canertinib Dihydrochloride
2.08
confidence
30
Tirabrutinib
1.95
confidence
31
Varlitinib
1.79
confidence
32
Ac 480
1.79
confidence
297+
studies
1.39
confidence
299+
studies
1.10
confidence
117+
studies
0.69
confidence
4+
studies
0.69
confidence

The compounds above were identified through computational analysis of BindingDB binding assay data and PubMed literature for ERBB4 (erb-b2 receptor tyrosine kinase 4). Confidence scores reflect the strength and breadth of experimental evidence.

Explore related resources: ERBB4 target overview · All biological targets · Biological pathways

Data from BindingDB and PubMed. For research purposes only. Not medical advice.