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Compounds That Target ERCC2

General transcription and DNA repair factor IIH helicase subunit XPD · 118 compounds in BiohacksAI corpus

ERCC2 (General transcription and DNA repair factor IIH helicase subunit XPD) is a biological target with 118 documented compound interactions in the BiohacksAI corpus. The compounds listed below have been identified through computational analysis of BindingDB binding assay data and PubMed literature. Each interaction is ranked by confidence score reflecting the breadth and strength of experimental evidence. This resource supports research into ERCC2 modulation for therapeutic and biohacking applications.

Most Studied Compounds for ERCC2
500+
studies
500+
studies
500+
studies
500+
studies
499+
studies
300+
studies
All 50 Compounds — Ranked by Evidence
1
Seliciclib
4.91
confidence
2
Alvocidib
4.52
confidence
3
Dinaciclib
3.87
confidence
4
Bms 387032
3.47
confidence
5
Pf 03758309
3.00
confidence
6
Danusertib
2.94
confidence
7
Milciclib
2.77
confidence
8
Pf 00562271
2.77
confidence
9
Kw 2449
2.64
confidence
10
Zotiraciclib
2.56
confidence
11
Defactinib
2.48
confidence
12
Agastache Rugosa
1.00
confidence
500+
studies
1.00
confidence
14
Allium Tuberosum
1.00
confidence
15
Aloe Vera
1.00
confidence
16
Artemisia Argyi
1.00
confidence
17
Aster Tataricus
1.00
confidence
18
Atractylodes Macrocephala
1.00
confidence
19
Bombyx Mori
1.00
confidence
20
Bupleurum Chinense
1.00
confidence
499+
studies
1.00
confidence
22
Chaenomeles Speciosa
1.00
confidence
23
Citrus Reticulata
1.00
confidence
116+
studies
1.00
confidence
500+
studies
1.00
confidence
26
Cuscuta Chinensis
1.00
confidence
27
Cynomorium Songaricum
1.00
confidence
28
Fritillaria Cirrhosa
1.00
confidence
29
Gastrodia Elata
1.00
confidence
30
Glycine Max
1.00
confidence
31
Glycyrrhiza Uralensis
1.00
confidence
32
Ligusticum Chuanxiong
1.00
confidence
33
Litchi Chinensis
1.00
confidence
34
Lonicera Japonica
1.00
confidence
35
Morus Alba
1.00
confidence
1.00
confidence
300+
studies
1.00
confidence
38
Panax Notoginseng
1.00
confidence
39
Perilla Frutescens
1.00
confidence
40
Pinellia Ternata
1.00
confidence
1.00
confidence
42
Polygala Tenuifolia
1.00
confidence
43
Poria Cocos
1.00
confidence
500+
studies
1.00
confidence
45
Prunus Armeniaca
1.00
confidence
46
Prunus Persica
1.00
confidence
500+
studies
1.00
confidence
48
Rehmannia Glutinosa
1.00
confidence
49
Salvia Miltiorrhiza
1.00
confidence
50
Sanguisorba Officinalis
1.00
confidence

The compounds above were identified through computational analysis of BindingDB binding assay data and PubMed literature for ERCC2 (General transcription and DNA repair factor IIH helicase subunit XPD). Confidence scores reflect the strength and breadth of experimental evidence.

Explore related resources: ERCC2 target overview · All biological targets · Biological pathways

Data from BindingDB and PubMed. For research purposes only. Not medical advice.