Compounds That Target ESR2

estrogen receptor 2 · 289 compounds in BiohacksAI corpus

ESR2 (estrogen receptor 2) is a receptor that mediates ligand-dependent signaling relevant to physiology, behavior, and metabolism. The 289 compounds with documented ESR2 interactions span synthetic agonists, antagonists, and natural ligands identified through BindingDB binding assays and PubMed literature in the BiohacksAI corpus.

View ESR2 target page →UniProt: Q92731 ↗

Most Studied Compounds for ESR2

Genistein

300+

studies

Estrone

300+

studies

Daidzein

300+

studies

Ethinyl Estradiol

300+

studies

Apigenin

300+

studies

Dhea

300+

studies

Dehydroepiandrosterone

300+

studies

Kaempferol

300+

studies

Emodin

300+

studies

Estriol

300+

studies

All 50 Compounds — Ranked by Evidence

Tamoxifen

5.88

confidence

Raloxifene

4.77

confidence

Isoliquiritigenin

4.50

confidence

Coumaric Acid

4.42

confidence

Morin

4.28

confidence

Diethylstilbestrol

4.06

confidence

Emate

3.89

confidence

Genistein

300+

studies

3.74

confidence

Afimoxifene

3.69

confidence

Liquirtigenin

3.61

confidence

Fulvestrant

295+

studies

3.18

confidence

Estrone

300+

studies

3.04

confidence

Bithionol

2.89

confidence

Bazedoxifene

2.89

confidence

Coumestrol

2.83

confidence

Raloxifene Hydrochloride

2.77

confidence

Bisphenol A

2.71

confidence

Tamoxifen Citrate

2.71

confidence

Daidzein

300+

studies

2.56

confidence

Diarylpropionitrile

2.56

confidence

Anthraflavicacid

2.48

confidence

Sophoraflavanone B

2.48

confidence

Ethinyl Estradiol

300+

studies

2.30

confidence

Brilanestrant

2.30

confidence

Phenolphthalein

2.30

confidence

Alfatradiol

2.30

confidence

Elacestrant

2.30

confidence

Ethylparaben

2.20

confidence

Apigenin

300+

studies

2.08

confidence

Dhea

300+

studies

2.08

confidence

Resveratrol

298+

studies

2.08

confidence

Dehydroepiandrosterone

300+

studies

2.08

confidence

Lasofoxifene

2.08

confidence

Kaempferol

300+

studies

1.79

confidence

Emodin

300+

studies

1.79

confidence

Estriol

300+

studies

1.79

confidence

Norethindrone

300+

studies

1.79

confidence

Rotenone

300+

studies

1.79

confidence

Effusol

1.79

confidence

Androstenediol

300+

studies

1.61

confidence

Mestranol

300+

studies

1.61

confidence

Methyltestosterone

300+

studies

1.61

confidence

Nandrolonepolycyclic

1.61

confidence

17 Alpha Hydroxyprogesterone Caproate

287+

studies

1.39

confidence

Azacitidine

298+

studies

1.39

confidence

Azacytidine

298+

studies

1.39

confidence

Dactinomycin

297+

studies

1.39

confidence

Dihydrotestosterone

300+

studies

1.39

confidence

Estetrol

266+

studies

1.39

confidence

Lynestrenol

299+

studies

1.39

confidence

The compounds above were identified through computational analysis of BindingDB binding assay data and PubMed literature for ESR2 (estrogen receptor 2). Confidence scores reflect the strength and breadth of experimental evidence.

Explore related resources: ESR2 target overview · All biological targets · Biological pathways

Data from BindingDB and PubMed. For research purposes only. Not medical advice.