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BiohacksAI/Targets/ESRRA/Compounds

Compounds That Target ESRRA

estrogen related receptor alpha · 296 compounds in BiohacksAI corpus

ESRRA (estrogen related receptor alpha) is a receptor that mediates ligand-dependent signaling relevant to physiology, behavior, and metabolism. The 296 compounds with documented ESRRA interactions span synthetic agonists, antagonists, and natural ligands identified through BindingDB binding assays and PubMed literature in the BiohacksAI corpus.

View ESRRA target page →UniProt: P11474 ↗
Most Studied Compounds for ESRRA
1
Budesonide
1.0k+
studies
2
Simvastatin
1.0k+
studies
3
Genistein
300+
studies
4
Daidzein
300+
studies
5
Apigenin
300+
studies
6
Rotenone
300+
studies
7
Hexachlorophene
300+
studies
8
Melengestrol Acetate
300+
studies
9
Androstenedione
300+
studies
10
Bromodeoxyuridine
300+
studies
All 50 Compounds — Ranked by Evidence
1
Tamoxifen
5.88
confidence
2
Genistein
300+
studies
2.83
confidence
3
Resveratrol
298+
studies
2.71
confidence
4
Fulvestrant
295+
studies
2.64
confidence
5
Thiabendazole
299+
studies
2.56
confidence
6
Daidzein
300+
studies
2.48
confidence
7
Apigenin
300+
studies
2.40
confidence
8
Finasteride
296+
studies
2.40
confidence
9
Rotenone
300+
studies
2.40
confidence
10
Amethopterin
289+
studies
2.30
confidence
11
Disulfiram
297+
studies
2.30
confidence
12
Flutamide
298+
studies
2.30
confidence
13
Leflunomide
297+
studies
2.30
confidence
14
Niclosamideorganic
2.30
confidence
15
Chlorhexidine
299+
studies
2.20
confidence
16
Hexachlorophene
300+
studies
2.20
confidence
17
Azacitidine
298+
studies
2.08
confidence
18
Azacytidine
298+
studies
2.08
confidence
19
Clotrimazoleheterocyclic
2.08
confidence
20
Melengestrol Acetate
300+
studies
2.08
confidence
21
Reserpine
297+
studies
2.08
confidence
22
Methylene Blue
200+
studies
1.95
confidence
23
Androstenedione
300+
studies
1.95
confidence
24
Bromodeoxyuridine
300+
studies
1.95
confidence
25
Cycloheximide
300+
studies
1.95
confidence
26
Dihydrotestosterone
300+
studies
1.95
confidence
27
Ethidium Bromide
300+
studies
1.95
confidence
28
Lovastatin
300+
studies
1.95
confidence
29
Mg624
3+
studies
1.95
confidence
30
Nitrofurantoin
297+
studies
1.95
confidence
31
Budesonide
1.0k+
studies
1.79
confidence
32
Dhea
300+
studies
1.79
confidence
33
Progesterone
299+
studies
1.79
confidence
34
Propyl Gallate
261+
studies
1.79
confidence
35
17 Alpha Hydroxyprogesterone
300+
studies
1.79
confidence
36
Dehydroepiandrosterone
300+
studies
1.79
confidence
37
Medroxyprogesterone Acetate
299+
studies
1.79
confidence
38
Megestrol Acetate
300+
studies
1.79
confidence
39
Ouabain
300+
studies
1.79
confidence
40
Oxymetholone
298+
studies
1.79
confidence
41
Phenelzine Sulfate
2+
studies
1.79
confidence
42
Phenoxybenzamine Hydrochloride
21+
studies
1.79
confidence
43
Riluzole
298+
studies
1.79
confidence
44
Chrysinflavonoids
1.61
confidence
45
Simvastatin
1.0k+
studies
1.61
confidence
46
2 Acetylaminofluorene
300+
studies
1.61
confidence
47
6 Aminonicotinamide
300+
studies
1.61
confidence
48
Acetaldehyde
300+
studies
1.61
confidence
49
Amlexanox
96+
studies
1.61
confidence
50
Axitinib
298+
studies
1.61
confidence

The compounds above were identified through computational analysis of BindingDB binding assay data and PubMed literature for ESRRA (estrogen related receptor alpha). Confidence scores reflect the strength and breadth of experimental evidence.

Explore related resources: ESRRA target overview · All biological targets · Biological pathways

Data from BindingDB and PubMed. For research purposes only. Not medical advice.