BETABiohacksAI is a research tool for informational purposes only. All outputs are computational hypothesis candidates — not confirmed mechanisms, not medical advice, and not a substitute for professional medical judgment. Independent experimental validation is always required.
BiohacksAI is an evolving scientific literature platform. New compounds and evidence are indexed continuously.
B
○
BiohacksAI/Targets/FPGS/Compounds

Compounds That Target FPGS

folylpolyglutamate synthase · 119 compounds in BiohacksAI corpus

FPGS (folylpolyglutamate synthase) is a biological target with 119 documented compound interactions in the BiohacksAI corpus. The compounds listed below have been identified through computational analysis of BindingDB binding assay data and PubMed literature. Each interaction is ranked by confidence score reflecting the breadth and strength of experimental evidence. This resource supports research into FPGS modulation for therapeutic and biohacking applications.

View FPGS target page →UniProt: Q05932 ↗
Most Studied Compounds for FPGS
1
Curcuma Longa
500+
studies
2
Portulaca Oleracea
500+
studies
3
Centella Asiatica
499+
studies
4
Foeniculum Vulgare
499+
studies
5
Panax Ginseng
300+
studies
6
Ginkgo Biloba
299+
studies
7
Pemetrexed
299+
studies
8
Amethopterin
289+
studies
9
Rubia Cordifolia
200+
studies
10
Curculigo Orchioides
116+
studies
All 51 Compounds — Ranked by Evidence
1
Methotrexate
6.00
confidence
2
Amethopterin
289+
studies
1.10
confidence
3
Agastache Rugosa
1.00
confidence
4
Allium Tuberosum
1.00
confidence
5
Aloe Vera
1.00
confidence
6
Arctium Lappa
1.00
confidence
7
Artemisia Annua
1.00
confidence
8
Artemisia Argyi
1.00
confidence
9
Artemisia Capillaris
1.00
confidence
10
Aster Tataricus
1.00
confidence
11
Bupleurum Chinense
1.00
confidence
12
Centella Asiatica
499+
studies
1.00
confidence
13
Chaenomeles Speciosa
1.00
confidence
14
Citrus Reticulata
1.00
confidence
15
Crataegus Pinnatifida
1.00
confidence
16
Curculigo Orchioides
116+
studies
1.00
confidence
17
Curcuma Longa
500+
studies
1.00
confidence
18
Cuscuta Chinensis
1.00
confidence
19
Cynomorium Songaricum
1.00
confidence
20
Ephedra Sinica
1.00
confidence
21
Eriobotrya Japonica
1.00
confidence
22
Eucommia Ulmoides
1.00
confidence
23
Foeniculum Vulgare
499+
studies
1.00
confidence
24
Forsythia Suspensa
1.00
confidence
25
Fritillaria Cirrhosa
1.00
confidence
26
Gastrodia Elata
1.00
confidence
27
Ginkgo Biloba
299+
studies
1.00
confidence
28
Glycine Max
1.00
confidence
29
Glycyrrhiza Uralensis
1.00
confidence
30
Ligusticum Chuanxiong
1.00
confidence
31
Lilium Lancifolium
1.00
confidence
32
Lithospermum Erythrorhizon
1.00
confidence
33
Lobelia Chinensis
1.00
confidence
34
Lonicera Japonica
1.00
confidence
35
Magnolia Biondii
1.00
confidence
36
Morus Alba
1.00
confidence
37
Nelumbo Nucifera
1.00
confidence
38
Panax Ginseng
300+
studies
1.00
confidence
39
Perilla Frutescens
1.00
confidence
40
Pinellia Ternata
1.00
confidence
41
Polygonum Cuspidatum
1.00
confidence
42
Poria Cocos
1.00
confidence
43
Portulaca Oleracea
500+
studies
1.00
confidence
44
Prunella Vulgaris
1.00
confidence
45
Prunus Mume
1.00
confidence
46
Prunus Persica
1.00
confidence
47
Pulsatilla Chinensis
1.00
confidence
48
Rehmannia Glutinosa
1.00
confidence
49
Rubia Cordifolia
200+
studies
1.00
confidence
50
Achyranthes Bidentata
1.00
confidence
51
Pemetrexed
299+
studies
0.69
confidence

The compounds above were identified through computational analysis of BindingDB binding assay data and PubMed literature for FPGS (folylpolyglutamate synthase). Confidence scores reflect the strength and breadth of experimental evidence.

Explore related resources: FPGS target overview · All biological targets · Biological pathways

Data from BindingDB and PubMed. For research purposes only. Not medical advice.