BETABiohacksAI is a research tool for informational purposes only. All outputs are computational hypothesis candidates — not confirmed mechanisms, not medical advice, and not a substitute for professional medical judgment. Independent experimental validation is always required.
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BiohacksAI/Targets/GLI1/Compounds

Compounds That Target GLI1

GLI-Kruppel family member GLI1 · 108 compounds in BiohacksAI corpus

GLI1 (GLI-Kruppel family member GLI1) is a biological target with 108 documented compound interactions in the BiohacksAI corpus. The compounds listed below have been identified through computational analysis of BindingDB binding assay data and PubMed literature. Each interaction is ranked by confidence score reflecting the breadth and strength of experimental evidence. This resource supports research into GLI1 modulation for therapeutic and biohacking applications.

View GLI1 target page →UniProt: BAA85004 ↗
Most Studied Compounds for GLI1
1
Curcuma Longa
500+
studies
2
Allium Sativum
500+
studies
3
Centella Asiatica
499+
studies
4
Zingiber Officinale
498+
studies
5
Panax Ginseng
300+
studies
6
Cycloheximide
300+
studies
7
Vorinostat
299+
studies
8
Streptonigrin
299+
studies
9
Anisomycin
247+
studies
10
Calcimycin
216+
studies
All 50 Compounds — Ranked by Evidence
1
Betulinic Acid
5.21
confidence
2
Cyclopamine
3.50
confidence
3
Staurosporinone
2.77
confidence
4
Physalin B
2.64
confidence
5
Alphitolic Acid
2.48
confidence
6
Physalin F
2.40
confidence
7
Anisomycin
247+
studies
1.61
confidence
8
Cladribinenucleotide
1.61
confidence
9
Clofilium Tosylatedrugage
1.61
confidence
10
Dihydrorotenone
13+
studies
1.61
confidence
11
Vorinostat
299+
studies
1.39
confidence
12
Zingiber Officinale
498+
studies
1.00
confidence
13
Centella Asiatica
499+
studies
1.00
confidence
14
Chaenomeles Speciosa
1.00
confidence
15
Curcuma Longa
500+
studies
1.00
confidence
16
Eucommia Ulmoides
1.00
confidence
17
Forsythia Suspensa
1.00
confidence
18
Glycine Max
1.00
confidence
19
Glycyrrhiza Uralensis
1.00
confidence
20
Morus Alba
1.00
confidence
21
Nelumbo Nucifera
1.00
confidence
22
Panax Ginseng
300+
studies
1.00
confidence
23
Panax Notoginseng
1.00
confidence
24
Polygonum Cuspidatum
1.00
confidence
25
Rubia Cordifolia
200+
studies
1.00
confidence
26
Salvia Miltiorrhiza
1.00
confidence
27
Sanguisorba Officinalis
1.00
confidence
28
Scutellaria Baicalensis
1.00
confidence
29
Smilax Glabra
1.00
confidence
30
Vigna Umbellata
1.00
confidence
31
Tyrphostin 9
2+
studies
0.69
confidence
32
Calcimycin
216+
studies
0.69
confidence
33
Cycloheximide
300+
studies
0.69
confidence
34
Niclosamideorganic
0.69
confidence
35
Streptonigrin
299+
studies
0.69
confidence
36
Allium Sativum
500+
studies
0.50
confidence
37
Allium Tuberosum
0.50
confidence
38
Aloe Vera
0.50
confidence
39
Apis Mellifera
0.50
confidence
40
Aquilaria Sinensis
0.50
confidence
41
Arctium Lappa
0.50
confidence
42
Areca Catechu
199+
studies
0.50
confidence
43
Artemisia Annua
0.50
confidence
44
Aucklandia Lappa
0.50
confidence
45
Bombyx Mori
0.50
confidence
46
Belamcanda Chinensis
0.50
confidence
47
Achyranthes Bidentata
0.50
confidence
48
Albizia Julibrissin
0.50
confidence
49
Alisma Plantago
0.50
confidence
50
Allium Fistulosum
0.50
confidence

The compounds above were identified through computational analysis of BindingDB binding assay data and PubMed literature for GLI1 (GLI-Kruppel family member GLI1). Confidence scores reflect the strength and breadth of experimental evidence.

Explore related resources: GLI1 target overview · All biological targets · Biological pathways

Data from BindingDB and PubMed. For research purposes only. Not medical advice.