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BiohacksAI/Targets/GRIN1/Compounds

Compounds That Target GRIN1

glutamate ionotropic receptor NMDA type subunit 1 · 87 compounds in BiohacksAI corpus

GRIN1 (glutamate ionotropic receptor NMDA type subunit 1) is a receptor that mediates ligand-dependent signaling relevant to physiology, behavior, and metabolism. The 87 compounds with documented GRIN1 interactions span synthetic agonists, antagonists, and natural ligands identified through BindingDB binding assays and PubMed literature in the BiohacksAI corpus.

View GRIN1 target page →UniProt: Q05586 ↗
Most Studied Compounds for GRIN1
1
Allium Sativum
500+
studies
2
Curcuma Longa
500+
studies
3
Portulaca Oleracea
500+
studies
4
Zingiber Officinale
498+
studies
5
Glycine
300+
studies
6
Dextrorphan
300+
studies
7
Aspartic Acid
300+
studies
8
Ethidium Bromide
300+
studies
9
Kynurenic Acid
300+
studies
10
Phenformin
300+
studies
All 50 Compounds — Ranked by Evidence
1
Glutamate
297+
studies
3.40
confidence
2
Glutamic Acid
297+
studies
3.40
confidence
3
Glycine
300+
studies
2.77
confidence
4
Pentamidine
299+
studies
1.95
confidence
5
Dextromethorphan
296+
studies
1.79
confidence
6
Dextrorphan
300+
studies
1.79
confidence
7
Levorphanol
297+
studies
1.79
confidence
8
Cycloserine
298+
studies
1.61
confidence
9
Aspartic Acid
300+
studies
1.39
confidence
10
Eliprodil
33+
studies
1.39
confidence
11
Memantine Hydrochloride
34+
studies
1.39
confidence
12
D-Aspartic Acid
29+
studies
1.10
confidence
13
Ethidium Bromide
300+
studies
1.10
confidence
14
Kynurenic Acid
300+
studies
1.10
confidence
15
Allium Sativum
500+
studies
1.00
confidence
16
Aloe Vera
1.00
confidence
17
Bufo Bufo
1.00
confidence
18
Bupleurum Chinense
1.00
confidence
19
Curcuma Longa
500+
studies
1.00
confidence
20
Glycyrrhiza Uralensis
1.00
confidence
21
Morus Alba
1.00
confidence
22
Pinellia Ternata
1.00
confidence
23
Portulaca Oleracea
500+
studies
1.00
confidence
24
Rehmannia Glutinosa
1.00
confidence
25
Salvia Miltiorrhiza
1.00
confidence
26
Sanguisorba Officinalis
1.00
confidence
27
Trichosanthes Kirilowii
1.00
confidence
28
Zingiber Officinale
498+
studies
1.00
confidence
29
Phenformin
300+
studies
0.69
confidence
30
Carvedilol
296+
studies
0.69
confidence
31
Dextrothyroxine
134+
studies
0.69
confidence
32
Dizocilpine Maleate
300+
studies
0.69
confidence
33
Ibotenic Acid
300+
studies
0.69
confidence
34
Spermine
300+
studies
0.69
confidence
35
Achyranthes Bidentata
0.50
confidence
36
Aconitum Carmichaelii
0.50
confidence
37
Apis Mellifera
0.50
confidence
38
Aquilaria Sinensis
0.50
confidence
39
Arctium Lappa
0.50
confidence
40
Areca Catechu
199+
studies
0.50
confidence
41
Artemisia Annua
0.50
confidence
42
Asparagus Cochinchinensis
0.50
confidence
43
Atractylodes Macrocephala
0.50
confidence
44
Aucklandia Lappa
0.50
confidence
45
Belamcanda Chinensis
0.50
confidence
46
Bombyx Mori
0.50
confidence
47
Carthamus Tinctorius
0.50
confidence
48
Citrus Reticulata
0.50
confidence
49
Coix Lacryma
0.50
confidence
50
Corydalis Yanhusuo
0.50
confidence

The compounds above were identified through computational analysis of BindingDB binding assay data and PubMed literature for GRIN1 (glutamate ionotropic receptor NMDA type subunit 1). Confidence scores reflect the strength and breadth of experimental evidence.

Explore related resources: GRIN1 target overview · All biological targets · Biological pathways

Data from BindingDB and PubMed. For research purposes only. Not medical advice.