BETABiohacksAI is a research tool for informational purposes only. All outputs are computational hypothesis candidates — not confirmed mechanisms, not medical advice, and not a substitute for professional medical judgment. Independent experimental validation is always required.
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BiohacksAI/Targets/GRM5/Compounds

Compounds That Target GRM5

glutamate metabotropic receptor 5 · 117 compounds in BiohacksAI corpus

GRM5 (glutamate metabotropic receptor 5) is a receptor that mediates ligand-dependent signaling relevant to physiology, behavior, and metabolism. The 117 compounds with documented GRM5 interactions span synthetic agonists, antagonists, and natural ligands identified through BindingDB binding assays and PubMed literature in the BiohacksAI corpus.

View GRM5 target page →UniProt: P41594 ↗
Most Studied Compounds for GRM5
1
Curcuma Longa
500+
studies
2
Portulaca Oleracea
500+
studies
3
Raphanus Sativus
500+
studies
4
Syzygium Aromaticum
500+
studies
5
Centella Asiatica
499+
studies
6
Panax Ginseng
300+
studies
7
Ginkgo Biloba
299+
studies
8
Glutamate
297+
studies
9
Glutamic Acid
297+
studies
10
Smilax China
142+
studies
All 50 Compounds — Ranked by Evidence
1
Quisqualate
3.09
confidence
2
Glutamate
297+
studies
2.94
confidence
3
Glutamic Acid
297+
studies
2.94
confidence
4
Fenobam Anhydrous
2.64
confidence
5
Bdb Whuutdbjxjrkmk
9+
studies
2.20
confidence
6
Agastache Rugosa
1.00
confidence
7
Allium Tuberosum
1.00
confidence
8
Aloe Vera
1.00
confidence
9
Apis Mellifera
1.00
confidence
10
Artemisia Capillaris
1.00
confidence
11
Aster Tataricus
1.00
confidence
12
Atractylodes Macrocephala
1.00
confidence
13
Bufo Bufo
1.00
confidence
14
Bupleurum Chinense
1.00
confidence
15
Carthamus Tinctorius
1.00
confidence
16
Centella Asiatica
499+
studies
1.00
confidence
17
Chaenomeles Speciosa
1.00
confidence
18
Citrus Reticulata
1.00
confidence
19
Curcuma Longa
500+
studies
1.00
confidence
20
Cuscuta Chinensis
1.00
confidence
21
Cynomorium Songaricum
1.00
confidence
22
Ephedra Sinica
1.00
confidence
23
Eriobotrya Japonica
1.00
confidence
24
Forsythia Suspensa
1.00
confidence
25
Gastrodia Elata
1.00
confidence
26
Ginkgo Biloba
299+
studies
1.00
confidence
27
Ligusticum Chuanxiong
1.00
confidence
28
Litchi Chinensis
1.00
confidence
29
Lithospermum Erythrorhizon
1.00
confidence
30
Lonicera Japonica
1.00
confidence
31
Morus Alba
1.00
confidence
32
Nelumbo Nucifera
1.00
confidence
33
Paeonia Lactiflora
1.00
confidence
34
Panax Ginseng
300+
studies
1.00
confidence
35
Panax Notoginseng
1.00
confidence
36
Perilla Frutescens
1.00
confidence
37
Pinellia Ternata
1.00
confidence
38
Piper Nigrum
1.00
confidence
39
Polygala Tenuifolia
1.00
confidence
40
Portulaca Oleracea
500+
studies
1.00
confidence
41
Prunus Armeniaca
1.00
confidence
42
Prunus Persica
1.00
confidence
43
Raphanus Sativus
500+
studies
1.00
confidence
44
Rehmannia Glutinosa
1.00
confidence
45
Salvia Miltiorrhiza
1.00
confidence
46
Scrophularia Ningpoensis
1.00
confidence
47
Scutellaria Baicalensis
1.00
confidence
48
Smilax China
142+
studies
1.00
confidence
49
Smilax Glabra
1.00
confidence
50
Syzygium Aromaticum
500+
studies
1.00
confidence

The compounds above were identified through computational analysis of BindingDB binding assay data and PubMed literature for GRM5 (glutamate metabotropic receptor 5). Confidence scores reflect the strength and breadth of experimental evidence.

Explore related resources: GRM5 target overview · All biological targets · Biological pathways

Data from BindingDB and PubMed. For research purposes only. Not medical advice.