BETABiohacksAI is a research tool for informational purposes only. All outputs are computational hypothesis candidates — not confirmed mechanisms, not medical advice, and not a substitute for professional medical judgment. Independent experimental validation is always required.
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BiohacksAI/Targets/HCN2/Compounds

Compounds That Target HCN2

hyperpolarization-activated, cyclic nucleotide-gated K+ 2 · 51 compounds in BiohacksAI corpus

HCN2 (hyperpolarization-activated, cyclic nucleotide-gated K+ 2) is a biological target with 51 documented compound interactions in the BiohacksAI corpus. The compounds listed below have been identified through computational analysis of BindingDB binding assay data and PubMed literature. Each interaction is ranked by confidence score reflecting the breadth and strength of experimental evidence. This resource supports research into HCN2 modulation for therapeutic and biohacking applications.

View HCN2 target page →UniProt: O88703 ↗
Most Studied Compounds for HCN2
1
Allium Sativum
500+
studies
2
Juglans Regia
500+
studies
3
Portulaca Oleracea
500+
studies
4
Zingiber Officinale
498+
studies
5
Cyclic Adenosine Monophosphate
300+
studies
6
Cyclic Amp
300+
studies
7
Cyclic Gmp
300+
studies
8
Panax Ginseng
300+
studies
9
Ginkgo Biloba
299+
studies
10
Ivabradine
293+
studies
All 50 Compounds — Ranked by Evidence
1
Ivabradine
293+
studies
1.10
confidence
2
Glycine Max
1.00
confidence
3
Glycyrrhiza Uralensis
1.00
confidence
4
Panax Notoginseng
1.00
confidence
5
Salvia Miltiorrhiza
1.00
confidence
6
Sanguisorba Officinalis
1.00
confidence
7
Zingiber Officinale
498+
studies
1.00
confidence
8
Ziziphus Jujuba
1.00
confidence
9
Clonidineheterocyclic
0.69
confidence
10
Cyclic Adenosine Monophosphate
300+
studies
0.69
confidence
11
Cyclic Amp
300+
studies
0.69
confidence
12
Cyclic Cmp
78+
studies
0.69
confidence
13
Cyclic Gmp
300+
studies
0.69
confidence
14
Achyranthes Bidentata
0.50
confidence
15
Aconitum Carmichaelii
0.50
confidence
16
Alisma Plantago
0.50
confidence
17
Allium Sativum
500+
studies
0.50
confidence
18
Aloe Vera
0.50
confidence
19
Apis Mellifera
0.50
confidence
20
Aquilaria Sinensis
0.50
confidence
21
Arctium Lappa
0.50
confidence
22
Belamcanda Chinensis
0.50
confidence
23
Bupleurum Chinense
0.50
confidence
24
Coix Lacryma
0.50
confidence
25
Ephedra Sinica
0.50
confidence
26
Epimedium Brevicornum
0.50
confidence
27
Eriobotrya Japonica
0.50
confidence
28
Eucommia Ulmoides
0.50
confidence
29
Forsythia Suspensa
0.50
confidence
30
Fritillaria Cirrhosa
0.50
confidence
31
Ginkgo Biloba
299+
studies
0.50
confidence
32
Juglans Regia
500+
studies
0.50
confidence
33
Ligusticum Chuanxiong
0.50
confidence
34
Lonicera Japonica
0.50
confidence
35
Mentha Haplocalyx
0.50
confidence
36
Morus Alba
0.50
confidence
37
Panax Ginseng
300+
studies
0.50
confidence
38
Pinellia Ternata
0.50
confidence
39
Poria Cocos
0.50
confidence
40
Portulaca Oleracea
500+
studies
0.50
confidence
41
Prunus Armeniaca
0.50
confidence
42
Prunus Mume
0.50
confidence
43
Scrophularia Ningpoensis
0.50
confidence
44
Scutellaria Baicalensis
0.50
confidence
45
Sophora Flavescens
0.50
confidence
46
Sophora Tonkinensis
0.50
confidence
47
Taraxacum Mongolicum
0.50
confidence
48
Trichosanthes Kirilowii
0.50
confidence
49
Tussilago Farfara
0.50
confidence
50
Vigna Radiata
0.50
confidence

The compounds above were identified through computational analysis of BindingDB binding assay data and PubMed literature for HCN2 (hyperpolarization-activated, cyclic nucleotide-gated K+ 2). Confidence scores reflect the strength and breadth of experimental evidence.

Explore related resources: HCN2 target overview · All biological targets · Biological pathways

Data from BindingDB and PubMed. For research purposes only. Not medical advice.