BETABiohacksAI is a research tool for informational purposes only. All outputs are computational hypothesis candidates — not confirmed mechanisms, not medical advice, and not a substitute for professional medical judgment. Independent experimental validation is always required.
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BiohacksAI/Targets/HDAC4/Compounds

Compounds That Target HDAC4

histone deacetylase 4 · 101 compounds in BiohacksAI corpus

HDAC4 (histone deacetylase 4) is a biological target with 101 documented compound interactions in the BiohacksAI corpus. The compounds listed below have been identified through computational analysis of BindingDB binding assay data and PubMed literature. Each interaction is ranked by confidence score reflecting the breadth and strength of experimental evidence. This resource supports research into HDAC4 modulation for therapeutic and biohacking applications.

View HDAC4 target page →UniProt: P56524 ↗
Most Studied Compounds for HDAC4
1
Curcuma Longa
500+
studies
2
Portulaca Oleracea
500+
studies
3
Zingiber Officinale
498+
studies
4
Trichostatin A
300+
studies
5
Butyric Acid
300+
studies
6
Ursolic Acid
300+
studies
7
Chlorogenic Acid
300+
studies
8
Camptothecin
300+
studies
9
Gamma Aminobutyric Acid
300+
studies
10
Vorinostat
299+
studies
All 53 Compounds — Ranked by Evidence
1
Trichostatin
5.45
confidence
2
Vorinostat
299+
studies
4.93
confidence
3
Entinostat
4.88
confidence
4
Tubastatin A
4.65
confidence
5
Trichostatin A
300+
studies
4.57
confidence
6
Panobinostat
4.26
confidence
7
Ricolinostat
4.08
confidence
8
Romidepsin
3.95
confidence
9
Belinostat
3.91
confidence
10
Apicidin
3.58
confidence
11
Tubacin
3.56
confidence
12
Largazole
3.26
confidence
13
Nexturastat A
3.14
confidence
14
Dacinostat
3.04
confidence
15
Quisinostat
2.94
confidence
16
Fimepinostat
2.89
confidence
17
Hinokitiol
2.89
confidence
18
Bendamustine
2.71
confidence
19
Scriptaid
53+
studies
2.71
confidence
20
Pracinostat
2.48
confidence
21
Cudc 101
2.40
confidence
22
Givinostat
2.30
confidence
23
Oxamflatin
2.20
confidence
24
Abexinostat
2.08
confidence
25
Aureusidin
2.08
confidence
26
Azumamide E
1.79
confidence
27
Pictilisibdrugage
1.61
confidence
28
Valproic Acid
296+
studies
1.61
confidence
29
Butyric Acid
300+
studies
1.10
confidence
30
Ursolic Acid
300+
studies
1.10
confidence
31
Artemisia Annua
1.00
confidence
32
Chaenomeles Speciosa
1.00
confidence
33
Crataegus Pinnatifida
1.00
confidence
34
Curcuma Longa
500+
studies
1.00
confidence
35
Epimedium Brevicornum
1.00
confidence
36
Ginkgo Biloba
299+
studies
1.00
confidence
37
Morus Alba
1.00
confidence
38
Nelumbo Nucifera
1.00
confidence
39
Portulaca Oleracea
500+
studies
1.00
confidence
40
Prunus Persica
1.00
confidence
41
Rehmannia Glutinosa
1.00
confidence
42
Scutellaria Baicalensis
1.00
confidence
43
Rubia Cordifolia
200+
studies
1.00
confidence
44
Zingiber Officinale
498+
studies
1.00
confidence
45
Ziziphus Jujuba
1.00
confidence
46
Agastache Rugosa
1.00
confidence
47
Areca Catechu
199+
studies
1.00
confidence
48
Bdb Chembl4244764
2+
studies
0.69
confidence
49
Daunorubicin
298+
studies
0.69
confidence
50
Celecoxib
295+
studies
0.69
confidence
51
Chlorogenic Acid
300+
studies
0.69
confidence
52
Camptothecin
300+
studies
0.69
confidence
53
Gamma Aminobutyric Acid
300+
studies
0.69
confidence

The compounds above were identified through computational analysis of BindingDB binding assay data and PubMed literature for HDAC4 (histone deacetylase 4). Confidence scores reflect the strength and breadth of experimental evidence.

Explore related resources: HDAC4 target overview · All biological targets · Biological pathways

Data from BindingDB and PubMed. For research purposes only. Not medical advice.