BETABiohacksAI is a research tool for informational purposes only. All outputs are computational hypothesis candidates — not confirmed mechanisms, not medical advice, and not a substitute for professional medical judgment. Independent experimental validation is always required.
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BiohacksAI/Targets/HDAC5/Compounds

Compounds That Target HDAC5

histone deacetylase 5 · 97 compounds in BiohacksAI corpus

HDAC5 (histone deacetylase 5) is a biological target with 97 documented compound interactions in the BiohacksAI corpus. The compounds listed below have been identified through computational analysis of BindingDB binding assay data and PubMed literature. Each interaction is ranked by confidence score reflecting the breadth and strength of experimental evidence. This resource supports research into HDAC5 modulation for therapeutic and biohacking applications.

View HDAC5 target page →UniProt: Q9UQL6 ↗
Most Studied Compounds for HDAC5
1
Curcuma Longa
500+
studies
2
Raphanus Sativus
500+
studies
3
Zingiber Officinale
498+
studies
4
Trichostatin A
300+
studies
5
Ursolic Acid
300+
studies
6
Butyric Acid
300+
studies
7
Chlorogenic Acid
300+
studies
8
Camptothecin
300+
studies
9
Gamma Aminobutyric Acid
300+
studies
10
Vorinostat
299+
studies
All 50 Compounds — Ranked by Evidence
1
Trichostatin
5.45
confidence
2
Vorinostat
299+
studies
4.92
confidence
3
Entinostat
4.88
confidence
4
Ebselen
4.74
confidence
5
Tubastatin A
4.65
confidence
6
Panobinostat
4.26
confidence
7
Trichostatin A
300+
studies
4.23
confidence
8
Ricolinostat
4.08
confidence
9
Romidepsin
3.95
confidence
10
Belinostat
3.91
confidence
11
Tubacin
3.56
confidence
12
Nexturastat A
3.14
confidence
13
Dacinostat
3.04
confidence
14
Quisinostat
2.94
confidence
15
Fimepinostat
2.89
confidence
16
Scriptaid
53+
studies
2.71
confidence
17
Bendamustine
2.71
confidence
18
Pracinostat
2.48
confidence
19
Suberohydroxamic Acid
2.48
confidence
20
Cudc 101
2.40
confidence
21
Givinostat
2.30
confidence
22
Abexinostat
2.08
confidence
23
Phenylbutyrylhydroxamic Acid
2.08
confidence
24
Azumamide E
1.79
confidence
25
Pictilisibdrugage
1.61
confidence
26
Valproic Acid
296+
studies
1.61
confidence
27
Ursolic Acid
300+
studies
1.10
confidence
28
Butyric Acid
300+
studies
1.10
confidence
29
Achyranthes Bidentata
1.00
confidence
30
Agastache Rugosa
1.00
confidence
31
Curcuma Longa
500+
studies
1.00
confidence
32
Epimedium Brevicornum
1.00
confidence
33
Morus Alba
1.00
confidence
34
Perilla Frutescens
1.00
confidence
35
Polygonum Cuspidatum
1.00
confidence
36
Prunus Armeniaca
1.00
confidence
37
Raphanus Sativus
500+
studies
1.00
confidence
38
Rehmannia Glutinosa
1.00
confidence
39
Salvia Miltiorrhiza
1.00
confidence
40
Stemona Sessilifolia
1.00
confidence
41
Taraxacum Mongolicum
1.00
confidence
42
Zingiber Officinale
498+
studies
1.00
confidence
43
Ziziphus Jujuba
1.00
confidence
44
Chlorogenic Acid
300+
studies
0.69
confidence
45
Camptothecin
300+
studies
0.69
confidence
46
Celecoxib
295+
studies
0.69
confidence
47
Daunorubicin
298+
studies
0.69
confidence
48
Gamma Aminobutyric Acid
300+
studies
0.69
confidence
49
Bdb Chembl4244764
2+
studies
0.69
confidence
50
Aconitum Carmichaelii
0.50
confidence

The compounds above were identified through computational analysis of BindingDB binding assay data and PubMed literature for HDAC5 (histone deacetylase 5). Confidence scores reflect the strength and breadth of experimental evidence.

Explore related resources: HDAC5 target overview · All biological targets · Biological pathways

Data from BindingDB and PubMed. For research purposes only. Not medical advice.