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Compounds That Target HDAC6

histone deacetylase 6 · 123 compounds in BiohacksAI corpus

HDAC6 (histone deacetylase 6) is a biological target with 123 documented compound interactions in the BiohacksAI corpus. The compounds listed below have been identified through computational analysis of BindingDB binding assay data and PubMed literature. Each interaction is ranked by confidence score reflecting the breadth and strength of experimental evidence. This resource supports research into HDAC6 modulation for therapeutic and biohacking applications.

Most Studied Compounds for HDAC6
300+
studies
299+
studies
53+
studies
All 50 Compounds — Ranked by Evidence
1
Trichostatin
5.45
confidence
299+
studies
5.32
confidence
300+
studies
5.02
confidence
4
Entinostat
4.88
confidence
5
Ebselen
4.74
confidence
6
Tubastatin A
4.65
confidence
7
Morin
4.28
confidence
8
Panobinostat
4.26
confidence
9
Dactolisib
4.25
confidence
10
Ruxolitinib
4.23
confidence
11
Ricolinostat
4.08
confidence
12
Urb 597
4.08
confidence
13
Formononetin
4.06
confidence
14
Piperine
4.04
confidence
15
Gentian Violet
4.03
confidence
16
Nitazoxanide
3.97
confidence
17
Romidepsin
3.95
confidence
18
Fluphenazine
3.91
confidence
19
Belinostat
3.91
confidence
20
Apabetalone
3.66
confidence
21
Apicidin
3.58
confidence
22
Diosmetin
3.58
confidence
23
Tubacin
3.56
confidence
24
6bio
3.50
confidence
25
Tryptanthrin
3.47
confidence
26
Linifanib
3.33
confidence
27
Irosustat
3.30
confidence
28
Mocetinostat
3.30
confidence
29
Benzohydroxamate
3.26
confidence
30
Largazole
3.26
confidence
31
Psammaplin A
3.18
confidence
32
Nexturastat A
3.14
confidence
33
Tideglusib
3.14
confidence
34
Rutaecarpine
3.09
confidence
35
Dacinostat
3.04
confidence
53+
studies
2.94
confidence
37
Quisinostat
2.94
confidence
38
Ku 55933
2.94
confidence
39
Citarinostat
2.94
confidence
40
Fimepinostat
2.89
confidence
41
Tanshinone I
2.89
confidence
42
Indoprofen
2.77
confidence
43
Bendamustine
2.71
confidence
44
Kw 2449
2.64
confidence
45
Fenobam Anhydrous
2.64
confidence
46
Flupentixol
2.56
confidence
47
Ataluren
2.56
confidence
48
Pracinostat
2.48
confidence
49
Suberohydroxamic Acid
2.48
confidence
50
Ipriflavone
2.48
confidence

The compounds above were identified through computational analysis of BindingDB binding assay data and PubMed literature for HDAC6 (histone deacetylase 6). Confidence scores reflect the strength and breadth of experimental evidence.

Explore related resources: HDAC6 target overview · All biological targets · Biological pathways

Data from BindingDB and PubMed. For research purposes only. Not medical advice.