BETABiohacksAI is a research tool for informational purposes only. All outputs are computational hypothesis candidates — not confirmed mechanisms, not medical advice, and not a substitute for professional medical judgment. Independent experimental validation is always required.
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BiohacksAI/Targets/HMGB1/Compounds

Compounds That Target HMGB1

high mobility group box 1 · 33 compounds in BiohacksAI corpus

HMGB1 (high mobility group box 1) is a biological target with 33 documented compound interactions in the BiohacksAI corpus. The compounds listed below have been identified through computational analysis of BindingDB binding assay data and PubMed literature. Each interaction is ranked by confidence score reflecting the breadth and strength of experimental evidence. This resource supports research into HMGB1 modulation for therapeutic and biohacking applications.

View HMGB1 target page →UniProt: P09429 ↗
Most Studied Compounds for HMGB1
1
Allium Sativum
500+
studies
2
Centella Asiatica
499+
studies
3
Zingiber Officinale
498+
studies
4
Panax Ginseng
300+
studies
5
Salicylic Acid
298+
studies
6
Amethopterin
289+
studies
All 33 Compounds — Ranked by Evidence
1
Methotrexate
6.00
confidence
2
Glycyrrhizin
3.95
confidence
3
Amethopterin
289+
studies
1.10
confidence
4
Salicylic Acid
298+
studies
1.10
confidence
5
Centella Asiatica
499+
studies
1.00
confidence
6
Cimicifuga Heracleifolia
1.00
confidence
7
Citrus Reticulata
1.00
confidence
8
Nelumbo Nucifera
1.00
confidence
9
Panax Ginseng
300+
studies
1.00
confidence
10
Rehmannia Glutinosa
1.00
confidence
11
Schisandra Chinensis
1.00
confidence
12
Zingiber Officinale
498+
studies
1.00
confidence
13
Allium Sativum
500+
studies
0.50
confidence
14
Aloe Vera
0.50
confidence
15
Artemisia Annua
0.50
confidence
16
Artemisia Capillaris
0.50
confidence
17
Aster Tataricus
0.50
confidence
18
Bletilla Striata
0.50
confidence
19
Carthamus Tinctorius
0.50
confidence
20
Commiphora Myrrha
0.50
confidence
21
Ephedra Sinica
0.50
confidence
22
Glycyrrhiza Uralensis
0.50
confidence
23
Inula Japonica
0.50
confidence
24
Mentha Haplocalyx
0.50
confidence
25
Paeonia Lactiflora
0.50
confidence
26
Pinellia Ternata
0.50
confidence
27
Piper Nigrum
0.50
confidence
28
Platycodon Grandiflorus
0.50
confidence
29
Poria Cocos
0.50
confidence
30
Prunus Armeniaca
0.50
confidence
31
Pulsatilla Chinensis
0.50
confidence
32
Sargassum Fusiforme
0.50
confidence
33
Vigna Radiata
0.50
confidence

The compounds above were identified through computational analysis of BindingDB binding assay data and PubMed literature for HMGB1 (high mobility group box 1). Confidence scores reflect the strength and breadth of experimental evidence.

Explore related resources: HMGB1 target overview · All biological targets · Biological pathways

Data from BindingDB and PubMed. For research purposes only. Not medical advice.