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Compounds That Target HRH1

histamine receptor H1 · 233 compounds in BiohacksAI corpus

HRH1 (histamine receptor H1) is a biological target with 233 documented compound interactions in the BiohacksAI corpus. The compounds listed below have been identified through computational analysis of BindingDB binding assay data and PubMed literature. Each interaction is ranked by confidence score reflecting the breadth and strength of experimental evidence. This resource supports research into HRH1 modulation for therapeutic and biohacking applications.

Most Studied Compounds for HRH1
994+
studies
300+
studies
298+
studies
298+
studies
296+
studies
296+
studies
All 50 Compounds — Ranked by Evidence
1
Clozapine
5.81
confidence
2
Imipramine
5.69
confidence
3
Risperidone
4.89
confidence
4
Terfenadine
4.55
confidence
5
Thioridazine
4.52
confidence
6
Olanzapine
4.44
confidence
7
Citalopram
4.36
confidence
8
Clomipramine
4.28
confidence
9
Diphenhydramine
4.22
confidence
10
Promazine
4.19
confidence
11
Pyrilamine
4.17
confidence
12
Ziprasidone
3.99
confidence
13
Ifenprodil
3.95
confidence
14
Fluphenazine
3.91
confidence
15
Fexofenadine
3.83
confidence
16
Ritanserin
3.61
confidence
17
Lysergide
3.61
confidence
18
Sertindole
3.58
confidence
19
Jnj 7777120
3.58
confidence
20
Doxepin
3.50
confidence
21
Pitolisant
3.50
confidence
22
Ketotifen
3.47
confidence
23
Mirtazapine
3.43
confidence
24
Prochlorperazine
3.33
confidence
25
Droperidol
3.30
confidence
26
Desloratadine
3.26
confidence
27
Azelastine
3.26
confidence
300+
studies
3.22
confidence
29
Chlorprothixene
3.00
confidence
30
Orphenadrine
2.94
confidence
31
Cariprazine
2.83
confidence
32
Paliperidone
2.71
confidence
33
Volinanserin
2.71
confidence
296+
studies
2.64
confidence
35
Ebastine
2.64
confidence
36
Niguldipine
2.56
confidence
37
Clemastine
2.56
confidence
38
Methapyrilene
2.56
confidence
39
Mizolastine
2.56
confidence
298+
studies
2.48
confidence
298+
studies
2.40
confidence
42
Penfluridol
2.40
confidence
43
Ketotifen Fumarate
2.40
confidence
44
Tolvaptan
2.40
confidence
994+
studies
2.30
confidence
46
Clorotepine
2.30
confidence
296+
studies
2.20
confidence
48
Silodosin
2.20
confidence
49
Mepazine
2.20
confidence
50
Fananserin
2.08
confidence

The compounds above were identified through computational analysis of BindingDB binding assay data and PubMed literature for HRH1 (histamine receptor H1). Confidence scores reflect the strength and breadth of experimental evidence.

Explore related resources: HRH1 target overview · All biological targets · Biological pathways

Data from BindingDB and PubMed. For research purposes only. Not medical advice.