BETABiohacksAI is a research tool for informational purposes only. All outputs are computational hypothesis candidates — not confirmed mechanisms, not medical advice, and not a substitute for professional medical judgment. Independent experimental validation is always required.
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BiohacksAI/Targets/HRH4/Compounds

Compounds That Target HRH4

histamine receptor H4 · 141 compounds in BiohacksAI corpus

HRH4 (histamine receptor H4) is a biological target with 141 documented compound interactions in the BiohacksAI corpus. The compounds listed below have been identified through computational analysis of BindingDB binding assay data and PubMed literature. Each interaction is ranked by confidence score reflecting the breadth and strength of experimental evidence. This resource supports research into HRH4 modulation for therapeutic and biohacking applications.

View HRH4 target page →UniProt: Q9H3N8 ↗
Most Studied Compounds for HRH4
1
Curcuma Longa
500+
studies
2
Histamine
300+
studies
3
Dimaprit
300+
studies
4
Impromidine
300+
studies
5
Panax Ginseng
300+
studies
6
Ginkgo Biloba
299+
studies
7
Pramipexole
297+
studies
8
Astemizole
280+
studies
9
Amoxapine
259+
studies
10
Burimamide
237+
studies
All 55 Compounds — Ranked by Evidence
1
Clozapine
5.81
confidence
2
Histamine
300+
studies
4.36
confidence
3
Thioperamide
4.25
confidence
4
Diphenhydramine
4.22
confidence
5
Pimozide
4.19
confidence
6
Jnj 7777120
3.58
confidence
7
Ketotifen
3.47
confidence
8
Clobenpropit
3.43
confidence
9
Desloratadine
3.26
confidence
10
Ciproxifan
3.18
confidence
11
Imetit
3.00
confidence
12
Immepip
2.77
confidence
13
Dimaprit
300+
studies
2.30
confidence
14
Iodoproxyfan
2.08
confidence
15
Imbutamine
1.95
confidence
16
Histamine Dihydrochloride
1.95
confidence
17
Impromidine
300+
studies
1.95
confidence
18
Isoloxapine
1.95
confidence
19
Impentamine
1.95
confidence
20
A 349821
1.79
confidence
21
4 Methylhistamine
1.79
confidence
22
Proxyfan
1.79
confidence
23
Burimamide
237+
studies
1.61
confidence
24
Loxapine
225+
studies
1.39
confidence
25
Panax Ginseng
300+
studies
1.00
confidence
26
Lithospermum Erythrorhizon
1.00
confidence
27
Lonicera Japonica
1.00
confidence
28
Morus Alba
1.00
confidence
29
Nelumbo Nucifera
1.00
confidence
30
Paeonia Lactiflora
1.00
confidence
31
Agastache Rugosa
1.00
confidence
32
Allium Tuberosum
1.00
confidence
33
Aloe Vera
1.00
confidence
34
Apis Mellifera
1.00
confidence
35
Artemisia Annua
1.00
confidence
36
Artemisia Capillaris
1.00
confidence
37
Aster Tataricus
1.00
confidence
38
Atractylodes Macrocephala
1.00
confidence
39
Bufo Bufo
1.00
confidence
40
Bupleurum Chinense
1.00
confidence
41
Citrus Reticulata
1.00
confidence
42
Curcuma Longa
500+
studies
1.00
confidence
43
Ephedra Sinica
1.00
confidence
44
Eriobotrya Japonica
1.00
confidence
45
Forsythia Suspensa
1.00
confidence
46
Fritillaria Cirrhosa
1.00
confidence
47
Gastrodia Elata
1.00
confidence
48
Ginkgo Biloba
299+
studies
1.00
confidence
49
Glycyrrhiza Uralensis
1.00
confidence
50
Litchi Chinensis
1.00
confidence
51
Metergoline
144+
studies
0.69
confidence
52
Astemizole
280+
studies
0.69
confidence
53
Amoxapine
259+
studies
0.69
confidence
54
Pramipexole
297+
studies
0.69
confidence
55
Bdb Qllzulwfesfqoy
2+
studies
0.69
confidence

The compounds above were identified through computational analysis of BindingDB binding assay data and PubMed literature for HRH4 (histamine receptor H4). Confidence scores reflect the strength and breadth of experimental evidence.

Explore related resources: HRH4 target overview · All biological targets · Biological pathways

Data from BindingDB and PubMed. For research purposes only. Not medical advice.