Compounds That Target HTR1B

5-hydroxytryptamine receptor 1B · 174 compounds in BiohacksAI corpus

HTR1B (5-hydroxytryptamine receptor 1B) is a receptor that mediates ligand-dependent signaling relevant to physiology, behavior, and metabolism. The 174 compounds with documented HTR1B interactions span synthetic agonists, antagonists, and natural ligands identified through BindingDB binding assays and PubMed literature in the BiohacksAI corpus.

View HTR1B target page →UniProt: P28564 ↗

Most Studied Compounds for HTR1B

Fluoxetine

1.0k+

studies

Quipazine

300+

studies

Mescaline

300+

studies

Methysergide

300+

studies

Mianserin

299+

studies

Pergolide

299+

studies

Ergotamine

299+

studies

Yohimbine

299+

studies

Dihydroergotamine

299+

studies

Lisuride

299+

studies

All 55 Compounds — Ranked by Evidence

Clozapine

5.81

confidence

Serotonin

5.47

confidence

8 Oh Dpat

4.98

confidence

Risperidone

4.89

confidence

Ketanserin

4.85

confidence

Olanzapine

4.44

confidence

Salmeterol

3.76

confidence

Ritanserin

3.61

confidence

Sertindole

3.58

confidence

Tryptamine

3.56

confidence

Way 100635

3.53

confidence

Sumatriptan

298+

studies

3.50

confidence

Mebufotenin

3.33

confidence

5 Methoxytryptamine

3.18

confidence

Zolmitriptan

3.18

confidence

Rizatriptan

3.00

confidence

Psilocin

2.77

confidence

Paliperidone

2.71

confidence

Niguldipine

2.56

confidence

Bay 293

2.48

confidence

Ketotifen Fumarate

2.40

confidence

Gr 127935

2.30

confidence

Quipazine

300+

studies

2.30

confidence

Xylometazoline

2.30

confidence

Naratriptan

2.30

confidence

Frovatriptan

2.30

confidence

Silodosin

2.20

confidence

Sb 258741

2.08

confidence

Nantenine

2.08

confidence

Mazapertine

1.95

confidence

Brexpiprazole

1.79

confidence

Mianserin

299+

studies

1.61

confidence

Metergoline

144+

studies

1.61

confidence

Pindololorganic

1.39

confidence

Pergolide

299+

studies

1.39

confidence

Ergotamine

299+

studies

1.39

confidence

Yohimbine

299+

studies

1.39

confidence

Dihydroergotamine

299+

studies

1.10

confidence

Lisuride

299+

studies

1.10

confidence

Mescaline

300+

studies

1.10

confidence

Methysergide

300+

studies

1.10

confidence

Oxymetazoline

298+

studies

1.10

confidence

Aripiprazole

298+

studies

1.10

confidence

Bufotenin

93+

studies

1.10

confidence

Dihydroergotamine Methanesulfonate

studies

1.10

confidence

Allium Tuberosum

1.00

confidence

Aloe Vera

1.00

confidence

Apis Mellifera

1.00

confidence

Artemisia Annua

1.00

confidence

Agastache Rugosa

1.00

confidence

Amitriptyline

299+

studies

0.69

confidence

Buspirone

299+

studies

0.69

confidence

Bromocriptine

299+

studies

0.69

confidence

Brl 15572

studies

0.69

confidence

Fluoxetine

1.0k+

studies

0.69

confidence

The compounds above were identified through computational analysis of BindingDB binding assay data and PubMed literature for HTR1B (5-hydroxytryptamine receptor 1B). Confidence scores reflect the strength and breadth of experimental evidence.

Explore related resources: HTR1B target overview · All biological targets · Biological pathways

Data from BindingDB and PubMed. For research purposes only. Not medical advice.