Compounds That Target HTR1D

5-hydroxytryptamine receptor 1D · 146 compounds in BiohacksAI corpus

HTR1D (5-hydroxytryptamine receptor 1D) is a receptor that mediates ligand-dependent signaling relevant to physiology, behavior, and metabolism. The 146 compounds with documented HTR1D interactions span synthetic agonists, antagonists, and natural ligands identified through BindingDB binding assays and PubMed literature in the BiohacksAI corpus.

View HTR1D target page →UniProt: P28565 ↗

Most Studied Compounds for HTR1D

Fluoxetine

1.0k+

studies

Quetiapine

994+

studies

Allium Sativum

500+

studies

Methysergide

300+

studies

Mescaline

300+

studies

Platelet Activating Factor

300+

studies

Yohimbine

299+

studies

Ergotamine

299+

studies

Mianserin

299+

studies

Dihydroergotamine

299+

studies

All 54 Compounds — Ranked by Evidence

Serotonin

5.47

confidence

Prazosin

5.15

confidence

8 Oh Dpat

4.98

confidence

Risperidone

4.89

confidence

Ketanserin

4.85

confidence

Salmeterol

3.76

confidence

Sumatriptan

298+

studies

3.74

confidence

Lysergide

3.61

confidence

Tryptamine

3.56

confidence

Mebufotenin

3.33

confidence

Purvalanola

3.18

confidence

Zolmitriptan

3.18

confidence

5 Methoxytryptamine

3.18

confidence

Rizatriptan

3.00

confidence

Psilocin

2.77

confidence

Paliperidone

2.71

confidence

Bay 293

2.48

confidence

Gsk046

2.40

confidence

Latrepirdine

2.40

confidence

Penfluridol

2.40

confidence

Xylometazoline

2.30

confidence

Loperamide Hydrochloride

2.30

confidence

Gr 127935

2.30

confidence

Sb 258719

2.30

confidence

Naratriptan

2.30

confidence

Frovatriptan

2.30

confidence

Silodosin

2.20

confidence

Metergoline

144+

studies

2.20

confidence

Yohimbine

299+

studies

2.20

confidence

Nantenine

2.08

confidence

Ru 24969

2.08

confidence

Sb 258741

2.08

confidence

Ergotamine

299+

studies

1.95

confidence

Brexpiprazole

1.79

confidence

Methysergide

300+

studies

1.61

confidence

Mianserin

299+

studies

1.61

confidence

Oxymetazoline

298+

studies

1.39

confidence

Dihydroergotamine

299+

studies

1.39

confidence

Bufotenin

93+

studies

1.39

confidence

Pergolide

299+

studies

1.39

confidence

Fluspirilene

74+

studies

1.10

confidence

Mescaline

300+

studies

1.10

confidence

Pindololorganic

1.10

confidence

Platelet Activating Factor

300+

studies

1.10

confidence

Aripiprazole

298+

studies

1.10

confidence

Lysergic Acid Diethylamide

298+

studies

1.10

confidence

Allium Sativum

500+

studies

1.00

confidence

Arctium Lappa

1.00

confidence

Bufo Bufo

1.00

confidence

Aloe Vera

1.00

confidence

Amitriptyline

299+

studies

0.69

confidence

Quetiapine

994+

studies

0.69

confidence

Fluoxetine

1.0k+

studies

0.69

confidence

Brl 15572

studies

0.69

confidence

The compounds above were identified through computational analysis of BindingDB binding assay data and PubMed literature for HTR1D (5-hydroxytryptamine receptor 1D). Confidence scores reflect the strength and breadth of experimental evidence.

Explore related resources: HTR1D target overview · All biological targets · Biological pathways

Data from BindingDB and PubMed. For research purposes only. Not medical advice.