Compounds That Target HTR1E

5-hydroxytryptamine receptor 1E · 139 compounds in BiohacksAI corpus

HTR1E (5-hydroxytryptamine receptor 1E) is a receptor that mediates ligand-dependent signaling relevant to physiology, behavior, and metabolism. The 139 compounds with documented HTR1E interactions span synthetic agonists, antagonists, and natural ligands identified through BindingDB binding assays and PubMed literature in the BiohacksAI corpus.

View HTR1E target page →UniProt: P28566 ↗

Most Studied Compounds for HTR1E

Quetiapine

994+

studies

Curcuma Longa

500+

studies

Methysergide

300+

studies

Panax Ginseng

300+

studies

Phentolamine

300+

studies

Mescaline

300+

studies

Ergotamine

299+

studies

Yohimbine

299+

studies

Ergonovine

299+

studies

Dihydroergotamine

299+

studies

All 57 Compounds — Ranked by Evidence

Clozapine

5.81

confidence

Serotonin

5.47

confidence

Lysergide

3.61

confidence

Ritanserin

3.61

confidence

Psilocin

2.77

confidence

Sumatriptan

298+

studies

2.48

confidence

Latrepirdine

2.40

confidence

Methysergide

300+

studies

2.40

confidence

Metergoline

144+

studies

2.20

confidence

Brexpiprazole

1.79

confidence

Methylergonovine

193+

studies

1.61

confidence

Ergotamine

299+

studies

1.61

confidence

Quetiapine

994+

studies

1.10

confidence

Yohimbine

299+

studies

1.10

confidence

Lysergic Acid Diethylamide

298+

studies

1.10

confidence

Fluspirilene

74+

studies

1.10

confidence

Ergonovine

299+

studies

1.10

confidence

Dihydroergotamine Methanesulfonate

studies

1.10

confidence

Dihydroergotamine

299+

studies

1.10

confidence

Brl 15572

studies

1.10

confidence

Polygala Tenuifolia

1.00

confidence

Morus Alba

1.00

confidence

Nelumbo Nucifera

1.00

confidence

Paeonia Lactiflora

1.00

confidence

Panax Ginseng

300+

studies

1.00

confidence

Panax Notoginseng

1.00

confidence

Perilla Frutescens

1.00

confidence

Pinellia Ternata

1.00

confidence

Agastache Rugosa

1.00

confidence

Allium Tuberosum

1.00

confidence

Aloe Vera

1.00

confidence

Apis Mellifera

1.00

confidence

Artemisia Annua

1.00

confidence

Artemisia Capillaris

1.00

confidence

Aster Tataricus

1.00

confidence

Atractylodes Macrocephala

1.00

confidence

Bufo Bufo

1.00

confidence

Bupleurum Chinense

1.00

confidence

Citrus Reticulata

1.00

confidence

Curcuma Longa

500+

studies

1.00

confidence

Ephedra Sinica

1.00

confidence

Eriobotrya Japonica

1.00

confidence

Forsythia Suspensa

1.00

confidence

Fritillaria Cirrhosa

1.00

confidence

Gastrodia Elata

1.00

confidence

Ginkgo Biloba

299+

studies

1.00

confidence

Glycyrrhiza Uralensis

1.00

confidence

Litchi Chinensis

1.00

confidence

Lithospermum Erythrorhizon

1.00

confidence

Lonicera Japonica

1.00

confidence

Vinblastine Sulfate

81+

studies

0.69

confidence

Triflupromazine Hydrochloride

12+

studies

0.69

confidence

Podofilox

14+

studies

0.69

confidence

Pindololorganic

0.69

confidence

Phentolamine

300+

studies

0.69

confidence

Mescaline

300+

studies

0.69

confidence

Lisuride

299+

studies

0.69

confidence

The compounds above were identified through computational analysis of BindingDB binding assay data and PubMed literature for HTR1E (5-hydroxytryptamine receptor 1E). Confidence scores reflect the strength and breadth of experimental evidence.

Explore related resources: HTR1E target overview · All biological targets · Biological pathways

Data from BindingDB and PubMed. For research purposes only. Not medical advice.