BETABiohacksAI is a research tool for informational purposes only. All outputs are computational hypothesis candidates — not confirmed mechanisms, not medical advice, and not a substitute for professional medical judgment. Independent experimental validation is always required.
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BiohacksAI/Targets/HTR1F/Compounds

Compounds That Target HTR1F

5-hydroxytryptamine receptor 1F · 134 compounds in BiohacksAI corpus

HTR1F (5-hydroxytryptamine receptor 1F) is a receptor that mediates ligand-dependent signaling relevant to physiology, behavior, and metabolism. The 134 compounds with documented HTR1F interactions span synthetic agonists, antagonists, and natural ligands identified through BindingDB binding assays and PubMed literature in the BiohacksAI corpus.

View HTR1F target page →UniProt: P30940 ↗
Most Studied Compounds for HTR1F
1
Quetiapine
994+
studies
2
Curcuma Longa
500+
studies
3
Portulaca Oleracea
500+
studies
4
Raphanus Sativus
500+
studies
5
Methysergide
300+
studies
6
Mescaline
300+
studies
7
Panax Ginseng
300+
studies
8
Dihydroergotamine
299+
studies
9
Ergotamine
299+
studies
10
Yohimbine
299+
studies
All 50 Compounds — Ranked by Evidence
1
Sumatriptan
298+
studies
2.56
confidence
2
Metergoline
144+
studies
2.08
confidence
3
Methysergide
300+
studies
1.95
confidence
4
Dihydroergotamine
299+
studies
1.61
confidence
5
Ergotamine
299+
studies
1.61
confidence
6
Yohimbine
299+
studies
1.61
confidence
7
Mianserin
299+
studies
1.10
confidence
8
Quetiapine
994+
studies
1.10
confidence
9
Brl 15572
2+
studies
1.10
confidence
10
Mescaline
300+
studies
1.10
confidence
11
Methylergonovine
193+
studies
1.10
confidence
12
Pergolide
299+
studies
1.10
confidence
13
Agastache Rugosa
1.00
confidence
14
Allium Tuberosum
1.00
confidence
15
Aloe Vera
1.00
confidence
16
Apis Mellifera
1.00
confidence
17
Artemisia Annua
1.00
confidence
18
Artemisia Capillaris
1.00
confidence
19
Aster Tataricus
1.00
confidence
20
Atractylodes Macrocephala
1.00
confidence
21
Bombyx Mori
1.00
confidence
22
Bufo Bufo
1.00
confidence
23
Bupleurum Chinense
1.00
confidence
24
Citrus Reticulata
1.00
confidence
25
Curcuma Longa
500+
studies
1.00
confidence
26
Ephedra Sinica
1.00
confidence
27
Eriobotrya Japonica
1.00
confidence
28
Forsythia Suspensa
1.00
confidence
29
Fritillaria Cirrhosa
1.00
confidence
30
Gastrodia Elata
1.00
confidence
31
Ginkgo Biloba
299+
studies
1.00
confidence
32
Glycyrrhiza Uralensis
1.00
confidence
33
Litchi Chinensis
1.00
confidence
34
Lithospermum Erythrorhizon
1.00
confidence
35
Lonicera Japonica
1.00
confidence
36
Morus Alba
1.00
confidence
37
Nelumbo Nucifera
1.00
confidence
38
Paeonia Lactiflora
1.00
confidence
39
Panax Ginseng
300+
studies
1.00
confidence
40
Panax Notoginseng
1.00
confidence
41
Perilla Frutescens
1.00
confidence
42
Pinellia Ternata
1.00
confidence
43
Polygala Tenuifolia
1.00
confidence
44
Portulaca Oleracea
500+
studies
1.00
confidence
45
Prunus Mume
1.00
confidence
46
Raphanus Sativus
500+
studies
1.00
confidence
47
Rehmannia Glutinosa
1.00
confidence
48
Schisandra Chinensis
1.00
confidence
49
Scutellaria Baicalensis
1.00
confidence
50
Smilax China
142+
studies
1.00
confidence

The compounds above were identified through computational analysis of BindingDB binding assay data and PubMed literature for HTR1F (5-hydroxytryptamine receptor 1F). Confidence scores reflect the strength and breadth of experimental evidence.

Explore related resources: HTR1F target overview · All biological targets · Biological pathways

Data from BindingDB and PubMed. For research purposes only. Not medical advice.