Compounds That Target HTR2A

5-hydroxytryptamine receptor 2A · 246 compounds in BiohacksAI corpus

HTR2A (5-hydroxytryptamine receptor 2A) is a receptor that mediates ligand-dependent signaling relevant to physiology, behavior, and metabolism. The 246 compounds with documented HTR2A interactions span synthetic agonists, antagonists, and natural ligands identified through BindingDB binding assays and PubMed literature in the BiohacksAI corpus.

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Most Studied Compounds for HTR2A

Mianserin

299+

studies

Aripiprazole

298+

studies

All 50 Compounds — Ranked by Evidence

Tamoxifen

5.88

confidence

Clozapine

5.81

confidence

Imipramine

5.69

confidence

Serotonin

5.47

confidence

Imatinib

5.47

confidence

Desipramine

5.23

confidence

Risperidone

4.89

confidence

Ketanserin

4.85

confidence

Ly 294002

4.84

confidence

Raloxifene

4.77

confidence

Quinacrine

4.63

confidence

Terfenadine

4.55

confidence

Propafenone

4.53

confidence

Thioridazine

4.52

confidence

Amiodarone

4.51

confidence

Olanzapine

4.44

confidence

Quinpirole

4.42

confidence

Clomipramine

4.28

confidence

Spiperone

4.23

confidence

Diphenhydramine

4.22

confidence

Promazine

4.19

confidence

Pyrilamine

4.17

confidence

Diethylstilbestrol

4.06

confidence

Gentian Violet

4.03

confidence

Ziprasidone

3.99

confidence

Fluphenazine

3.91

confidence

Salmeterol

3.76

confidence

Nefazodone

3.71

confidence

Metitepine

3.71

confidence

Ritanserin

3.61

confidence

Lysergide

3.61

confidence

Sertindole

3.58

confidence

Phenethylamine

3.53

confidence

Doxepin

3.50

confidence

L 365260

3.50

confidence

Ketotifen

3.47

confidence

Mirtazapine

3.43

confidence

Chlorophenylpiperazine

3.37

confidence

Prochlorperazine

3.33

confidence

Mebufotenin

3.33

confidence

Droperidol

3.30

confidence

Desloratadine

3.26

confidence

Ropinirole

3.26

confidence

L 745870

3.22

confidence

5 Methoxytryptamine

3.18

confidence

Mesulergine

3.18

confidence

Intepirdine

3.14

confidence

Mianserin

299+

studies

3.09

confidence

Aripiprazole

298+

studies

3.04

confidence

Ipsapirone

3.04

confidence

The compounds above were identified through computational analysis of BindingDB binding assay data and PubMed literature for HTR2A (5-hydroxytryptamine receptor 2A). Confidence scores reflect the strength and breadth of experimental evidence.

Explore related resources: HTR2A target overview · All biological targets · Biological pathways

Data from BindingDB and PubMed. For research purposes only. Not medical advice.