Compounds That Target HTR2B

5-hydroxytryptamine receptor 2B · 285 compounds in BiohacksAI corpus

HTR2B (5-hydroxytryptamine receptor 2B) is a receptor that mediates ligand-dependent signaling relevant to physiology, behavior, and metabolism. The 285 compounds with documented HTR2B interactions span synthetic agonists, antagonists, and natural ligands identified through BindingDB binding assays and PubMed literature in the BiohacksAI corpus.

View HTR2B target page →UniProt: P41595 ↗

All 50 Compounds — Ranked by Evidence

Tamoxifen

5.88

confidence

Clozapine

5.81

confidence

Serotonin

5.47

confidence

Tretinoin

5.16

confidence

Prazosin

5.15

confidence

Risperidone

4.89

confidence

Ketanserin

4.85

confidence

Ly 294002

4.84

confidence

Raloxifene

4.77

confidence

Berberine Chloride

4.56

confidence

Terfenadine

4.55

confidence

Propafenone

4.53

confidence

Thioridazine

4.52

confidence

Amiodarone

4.51

confidence

Olanzapine

4.44

confidence

Citalopram

4.36

confidence

Clomipramine

4.28

confidence

Spiperone

4.23

confidence

Diphenhydramine

4.22

confidence

Promazine

4.19

confidence

Pyrilamine

4.17

confidence

Benzbromarone

4.13

confidence

Diethylstilbestrol

4.06

confidence

Propofol

4.01

confidence

Ib Meca

4.01

confidence

Ziprasidone

3.99

confidence

Mexiletine

3.99

confidence

Namodenoson

3.95

confidence

Loperamide

3.93

confidence

Fluphenazine

3.91

confidence

Isotretinoin

3.66

confidence

Lysergide

3.61

confidence

Doxazosin

3.53

confidence

Doxepin

3.50

confidence

L 365260

3.50

confidence

Ketotifen

3.47

confidence

Chlorophenylpiperazine

3.37

confidence

Prochlorperazine

3.33

confidence

Mebufotenin

3.33

confidence

Droperidol

3.30

confidence

Desloratadine

3.26

confidence

Azelastine

3.26

confidence

Oxybutynin

3.22

confidence

Bp 897

3.18

confidence

Mesulergine

3.18

confidence

Xanomeline

3.18

confidence

Lorcaserin

3.00

confidence

Orphenadrine

2.94

confidence

Levopropranolol

2.94

confidence

Bithionol

2.89

confidence

The compounds above were identified through computational analysis of BindingDB binding assay data and PubMed literature for HTR2B (5-hydroxytryptamine receptor 2B). Confidence scores reflect the strength and breadth of experimental evidence.

Explore related resources: HTR2B target overview · All biological targets · Biological pathways

Data from BindingDB and PubMed. For research purposes only. Not medical advice.