Compounds That Target HTR3A

5-hydroxytryptamine receptor 3A · 146 compounds in BiohacksAI corpus

HTR3A (5-hydroxytryptamine receptor 3A) is a receptor that mediates ligand-dependent signaling relevant to physiology, behavior, and metabolism. The 146 compounds with documented HTR3A interactions span synthetic agonists, antagonists, and natural ligands identified through BindingDB binding assays and PubMed literature in the BiohacksAI corpus.

View HTR3A target page →UniProt: P46098 ↗

Most Studied Compounds for HTR3A

Amlodipine

1.0k+

studies

Allium Sativum

500+

studies

Curcuma Longa

500+

studies

Foeniculum Vulgare

499+

studies

Centella Asiatica

499+

studies

Quipazine

300+

studies

Mescaline

300+

studies

Octopamine

300+

studies

Ondansetron

299+

studies

Mianserin

299+

studies

All 58 Compounds — Ranked by Evidence

Clozapine

5.81

confidence

Olanzapine

4.44

confidence

Ondansetron

299+

studies

3.83

confidence

Tropisetron

3.58

confidence

Tyramine

3.53

confidence

Mirtazapine

3.43

confidence

Quipazine

300+

studies

3.26

confidence

Metoclopramide

297+

studies

3.09

confidence

Tegaserod

2.89

confidence

Alosetron

2.77

confidence

Ketotifen Fumarate

2.40

confidence

Zacopride

2.40

confidence

Pnu 282987

2.30

confidence

Palonosetron

2.30

confidence

Prucalopride

2.20

confidence

Gsk778

2.08

confidence

Aplysinopsin

2.08

confidence

Irdabisant

2.08

confidence

Mianserin

299+

studies

1.95

confidence

Encenicline

1.95

confidence

Brexpiprazole

1.79

confidence

Amitriptyline

299+

studies

1.10

confidence

Aripiprazole

298+

studies

1.10

confidence

Mescaline

300+

studies

1.10

confidence

Octopamine

300+

studies

1.10

confidence

Pergolide

299+

studies

1.10

confidence

Sumatriptan

298+

studies

1.10

confidence

Litchi Chinensis

1.00

confidence

Cynomorium Songaricum

1.00

confidence

Ephedra Sinica

1.00

confidence

Eucommia Ulmoides

1.00

confidence

Foeniculum Vulgare

499+

studies

1.00

confidence

Forsythia Suspensa

1.00

confidence

Fritillaria Cirrhosa

1.00

confidence

Ginkgo Biloba

299+

studies

1.00

confidence

Lilium Lancifolium

1.00

confidence

Allium Sativum

500+

studies

1.00

confidence

Aloe Vera

1.00

confidence

Apis Mellifera

1.00

confidence

Arctium Lappa

1.00

confidence

Artemisia Argyi

1.00

confidence

Artemisia Capillaris

1.00

confidence

Atractylodes Macrocephala

1.00

confidence

Bombyx Mori

1.00

confidence

Bufo Bufo

1.00

confidence

Bupleurum Chinense

1.00

confidence

Centella Asiatica

499+

studies

1.00

confidence

Chaenomeles Speciosa

1.00

confidence

Citrus Reticulata

1.00

confidence

Curcuma Longa

500+

studies

1.00

confidence

Amoxapine

259+

studies

0.69

confidence

Astemizole

280+

studies

0.69

confidence

Chlorhexidine

299+

studies

0.69

confidence

Cyproheptadine

299+

studies

0.69

confidence

Loxapine

225+

studies

0.69

confidence

Nortriptyline

295+

studies

0.69

confidence

Vortioxetine

294+

studies

0.69

confidence

Amlodipine

1.0k+

studies

0.69

confidence

The compounds above were identified through computational analysis of BindingDB binding assay data and PubMed literature for HTR3A (5-hydroxytryptamine receptor 3A). Confidence scores reflect the strength and breadth of experimental evidence.

Explore related resources: HTR3A target overview · All biological targets · Biological pathways

Data from BindingDB and PubMed. For research purposes only. Not medical advice.