BETABiohacksAI is a research tool for informational purposes only. All outputs are computational hypothesis candidates — not confirmed mechanisms, not medical advice, and not a substitute for professional medical judgment. Independent experimental validation is always required.
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BiohacksAI/Targets/HTR3B/Compounds

Compounds That Target HTR3B

5-hydroxytryptamine receptor 3B · 61 compounds in BiohacksAI corpus

HTR3B (5-hydroxytryptamine receptor 3B) is a receptor that mediates ligand-dependent signaling relevant to physiology, behavior, and metabolism. The 61 compounds with documented HTR3B interactions span synthetic agonists, antagonists, and natural ligands identified through BindingDB binding assays and PubMed literature in the BiohacksAI corpus.

View HTR3B target page →UniProt: O95264 ↗
Most Studied Compounds for HTR3B
1
Allium Sativum
500+
studies
2
Juglans Regia
500+
studies
3
Portulaca Oleracea
500+
studies
4
Quipazine
300+
studies
5
Mescaline
300+
studies
6
Panax Ginseng
300+
studies
7
Ondansetron
299+
studies
8
Mianserin
299+
studies
9
Pergolide
299+
studies
10
Amitriptyline
299+
studies
All 50 Compounds — Ranked by Evidence
1
Ondansetron
299+
studies
3.66
confidence
2
Quipazine
300+
studies
3.09
confidence
3
Metoclopramide
297+
studies
3.04
confidence
4
Palonosetron
2.30
confidence
5
Mianserin
299+
studies
1.61
confidence
6
Mescaline
300+
studies
1.10
confidence
7
Pergolide
299+
studies
1.10
confidence
8
Aloe Vera
1.00
confidence
9
Bufo Bufo
1.00
confidence
10
Bupleurum Chinense
1.00
confidence
11
Morus Alba
1.00
confidence
12
Panax Ginseng
300+
studies
1.00
confidence
13
Panax Notoginseng
1.00
confidence
14
Pinellia Ternata
1.00
confidence
15
Rehmannia Glutinosa
1.00
confidence
16
Trichosanthes Kirilowii
1.00
confidence
17
Amitriptyline
299+
studies
0.69
confidence
18
Aripiprazole
298+
studies
0.69
confidence
19
Cyproheptadine
299+
studies
0.69
confidence
20
Nortriptyline
295+
studies
0.69
confidence
21
Sumatriptan
298+
studies
0.69
confidence
22
Aconitum Carmichaelii
0.50
confidence
23
Allium Sativum
500+
studies
0.50
confidence
24
Apis Mellifera
0.50
confidence
25
Arctium Lappa
0.50
confidence
26
Areca Catechu
199+
studies
0.50
confidence
27
Atractylodes Macrocephala
0.50
confidence
28
Aucklandia Lappa
0.50
confidence
29
Carthamus Tinctorius
0.50
confidence
30
Citrus Reticulata
0.50
confidence
31
Coix Lacryma
0.50
confidence
32
Corydalis Yanhusuo
0.50
confidence
33
Eriobotrya Japonica
0.50
confidence
34
Eucommia Ulmoides
0.50
confidence
35
Euryale Ferox
0.50
confidence
36
Forsythia Suspensa
0.50
confidence
37
Ginkgo Biloba
299+
studies
0.50
confidence
38
Glycine Max
0.50
confidence
39
Hirudo Nipponia
0.50
confidence
40
Inula Japonica
0.50
confidence
41
Juglans Regia
500+
studies
0.50
confidence
42
Leonurus Japonicus
0.50
confidence
43
Ligusticum Chuanxiong
0.50
confidence
44
Nelumbo Nucifera
0.50
confidence
45
Piper Nigrum
0.50
confidence
46
Polygala Tenuifolia
0.50
confidence
47
Polygonum Cuspidatum
0.50
confidence
48
Poria Cocos
0.50
confidence
49
Portulaca Oleracea
500+
studies
0.50
confidence
50
Sargassum Fusiforme
0.50
confidence

The compounds above were identified through computational analysis of BindingDB binding assay data and PubMed literature for HTR3B (5-hydroxytryptamine receptor 3B). Confidence scores reflect the strength and breadth of experimental evidence.

Explore related resources: HTR3B target overview · All biological targets · Biological pathways

Data from BindingDB and PubMed. For research purposes only. Not medical advice.