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BiohacksAI/Targets/HTR4/Compounds

Compounds That Target HTR4

5-hydroxytryptamine receptor 4 · 15 compounds in BiohacksAI corpus

HTR4 (5-hydroxytryptamine receptor 4) is a receptor that mediates ligand-dependent signaling relevant to physiology, behavior, and metabolism. The 15 compounds with documented HTR4 interactions span synthetic agonists, antagonists, and natural ligands identified through BindingDB binding assays and PubMed literature in the BiohacksAI corpus.

View HTR4 target page →UniProt: Q13639 ↗
Most Studied Compounds for HTR4
1
Mescaline
300+
studies
2
Pergolide
299+
studies
3
Mianserin
299+
studies
4
Amitriptyline
299+
studies
5
Cyproheptadine
299+
studies
6
Ondansetron
299+
studies
7
Metoclopramide
297+
studies
8
Nortriptyline
295+
studies
9
Metergoline
144+
studies
All 15 Compounds — Ranked by Evidence
1
Serotonin
5.47
confidence
2
Tropisetron
3.58
confidence
3
Rel Cisapride
3.40
confidence
4
5 Methoxytryptamine
3.18
confidence
5
Tegaserod
2.89
confidence
6
Metoclopramide
297+
studies
2.20
confidence
7
Prucalopride
2.20
confidence
8
Mescaline
300+
studies
1.10
confidence
9
Pergolide
299+
studies
1.10
confidence
10
Mianserin
299+
studies
0.69
confidence
11
Amitriptyline
299+
studies
0.69
confidence
12
Cyproheptadine
299+
studies
0.69
confidence
13
Metergoline
144+
studies
0.69
confidence
14
Nortriptyline
295+
studies
0.69
confidence
15
Ondansetron
299+
studies
0.69
confidence

The compounds above were identified through computational analysis of BindingDB binding assay data and PubMed literature for HTR4 (5-hydroxytryptamine receptor 4). Confidence scores reflect the strength and breadth of experimental evidence.

Explore related resources: HTR4 target overview · All biological targets · Biological pathways

Data from BindingDB and PubMed. For research purposes only. Not medical advice.