BETABiohacksAI is a research tool for informational purposes only. All outputs are computational hypothesis candidates — not confirmed mechanisms, not medical advice, and not a substitute for professional medical judgment. Independent experimental validation is always required.
BiohacksAI is an evolving scientific literature platform. New compounds and evidence are indexed continuously.
B

Compounds That Target HTR7

5-hydroxytryptamine receptor 7 · 208 compounds in BiohacksAI corpus

HTR7 (5-hydroxytryptamine receptor 7) is a receptor that mediates ligand-dependent signaling relevant to physiology, behavior, and metabolism. The 208 compounds with documented HTR7 interactions span synthetic agonists, antagonists, and natural ligands identified through BindingDB binding assays and PubMed literature in the BiohacksAI corpus.

Most Studied Compounds for HTR7
299+
studies
299+
studies
298+
studies
144+
studies
All 50 Compounds — Ranked by Evidence
1
Clozapine
5.81
confidence
2
Serotonin
5.47
confidence
3
8 Oh Dpat
4.98
confidence
4
Risperidone
4.89
confidence
5
Ketanserin
4.85
confidence
6
Thioridazine
4.52
confidence
7
Olanzapine
4.44
confidence
8
Spiperone
4.23
confidence
9
Ziprasidone
3.99
confidence
10
Fluphenazine
3.91
confidence
11
Salmeterol
3.76
confidence
12
Metitepine
3.71
confidence
13
Ritanserin
3.61
confidence
14
Lysergide
3.61
confidence
15
Tryptamine
3.56
confidence
16
Way 100635
3.53
confidence
17
Mirtazapine
3.43
confidence
18
Chlorophenylpiperazine
3.37
confidence
19
Nan 190
3.37
confidence
20
Mebufotenin
3.33
confidence
21
L 745870
3.22
confidence
22
5 Methoxytryptamine
3.18
confidence
23
Mesulergine
3.18
confidence
24
Scutellarin
3.18
confidence
25
Intepirdine
3.14
confidence
26
Ipsapirone
3.04
confidence
27
5 Oh Dpat
2.89
confidence
28
Cariprazine
2.83
confidence
29
Psilocin
2.77
confidence
30
Vilazodone
2.77
confidence
31
Paliperidone
2.71
confidence
32
Niguldipine
2.56
confidence
33
Idalopirdine
2.56
confidence
299+
studies
2.48
confidence
298+
studies
2.48
confidence
144+
studies
2.48
confidence
37
Bay 293
2.48
confidence
38
Latrepirdine
2.40
confidence
39
Ketotifen Fumarate
2.40
confidence
40
Clonidine Hydrochloride
2.40
confidence
41
Glaucine
2.30
confidence
42
Sb 258719
2.30
confidence
43
Silodosin
2.20
confidence
44
Rs Ifenprodil
2.20
confidence
45
Pizotyline
2.20
confidence
46
Oxitriptan
2.20
confidence
299+
studies
2.08
confidence
48
Nantenine
2.08
confidence
49
Fananserin
2.08
confidence
50
Sb 258741
2.08
confidence

The compounds above were identified through computational analysis of BindingDB binding assay data and PubMed literature for HTR7 (5-hydroxytryptamine receptor 7). Confidence scores reflect the strength and breadth of experimental evidence.

Explore related resources: HTR7 target overview · All biological targets · Biological pathways

Data from BindingDB and PubMed. For research purposes only. Not medical advice.