BETABiohacksAI is a research tool for informational purposes only. All outputs are computational hypothesis candidates — not confirmed mechanisms, not medical advice, and not a substitute for professional medical judgment. Independent experimental validation is always required.
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BiohacksAI/Targets/HTRA2/Compounds

Compounds That Target HTRA2

HTRA2 · 107 compounds in BiohacksAI corpus

HTRA2 (HTRA2) is a receptor that mediates ligand-dependent signaling relevant to physiology, behavior, and metabolism. The 107 compounds with documented HTRA2 interactions span synthetic agonists, antagonists, and natural ligands identified through BindingDB binding assays and PubMed literature in the BiohacksAI corpus.

View HTRA2 target page →
Most Studied Compounds for HTRA2
1
Allium Sativum
500+
studies
2
Curcuma Longa
500+
studies
3
Portulaca Oleracea
500+
studies
4
Centella Asiatica
499+
studies
5
Foeniculum Vulgare
499+
studies
6
Zingiber Officinale
498+
studies
7
Panax Ginseng
300+
studies
8
Ginkgo Biloba
299+
studies
9
Rubia Cordifolia
200+
studies
10
Areca Catechu
199+
studies
All 50 Compounds — Ranked by Evidence
1
Agastache Rugosa
1.00
confidence
2
Allium Sativum
500+
studies
1.00
confidence
3
Aloe Vera
1.00
confidence
4
Areca Catechu
199+
studies
1.00
confidence
5
Artemisia Annua
1.00
confidence
6
Atractylodes Macrocephala
1.00
confidence
7
Bupleurum Chinense
1.00
confidence
8
Carthamus Tinctorius
1.00
confidence
9
Centella Asiatica
499+
studies
1.00
confidence
10
Chaenomeles Speciosa
1.00
confidence
11
Citrus Reticulata
1.00
confidence
12
Crataegus Pinnatifida
1.00
confidence
13
Curcuma Longa
500+
studies
1.00
confidence
14
Eriobotrya Japonica
1.00
confidence
15
Eucommia Ulmoides
1.00
confidence
16
Foeniculum Vulgare
499+
studies
1.00
confidence
17
Fritillaria Cirrhosa
1.00
confidence
18
Gastrodia Elata
1.00
confidence
19
Ginkgo Biloba
299+
studies
1.00
confidence
20
Glycyrrhiza Uralensis
1.00
confidence
21
Lithospermum Erythrorhizon
1.00
confidence
22
Lobelia Chinensis
1.00
confidence
23
Lonicera Japonica
1.00
confidence
24
Morus Alba
1.00
confidence
25
Nelumbo Nucifera
1.00
confidence
26
Panax Ginseng
300+
studies
1.00
confidence
27
Panax Notoginseng
1.00
confidence
28
Perilla Frutescens
1.00
confidence
29
Portulaca Oleracea
500+
studies
1.00
confidence
30
Prunella Vulgaris
1.00
confidence
31
Prunus Mume
1.00
confidence
32
Prunus Persica
1.00
confidence
33
Rehmannia Glutinosa
1.00
confidence
34
Rubia Cordifolia
200+
studies
1.00
confidence
35
Schisandra Chinensis
1.00
confidence
36
Scutellaria Baicalensis
1.00
confidence
37
Smilax China
142+
studies
1.00
confidence
38
Smilax Glabra
1.00
confidence
39
Taraxacum Mongolicum
1.00
confidence
40
Vigna Umbellata
1.00
confidence
41
Zingiber Officinale
498+
studies
1.00
confidence
42
Ziziphus Jujuba
1.00
confidence
43
Achyranthes Bidentata
0.50
confidence
44
Aconitum Carmichaelii
0.50
confidence
45
Albizia Julibrissin
0.50
confidence
46
Alisma Plantago
0.50
confidence
47
Allium Fistulosum
0.50
confidence
48
Allium Tuberosum
0.50
confidence
49
Anemarrhena Asphodeloides
0.50
confidence
50
Apis Mellifera
0.50
confidence

The compounds above were identified through computational analysis of BindingDB binding assay data and PubMed literature for HTRA2 (HTRA2). Confidence scores reflect the strength and breadth of experimental evidence.

Explore related resources: HTRA2 target overview · All biological targets · Biological pathways

Data from BindingDB and PubMed. For research purposes only. Not medical advice.