BETABiohacksAI is a research tool for informational purposes only. All outputs are computational hypothesis candidates — not confirmed mechanisms, not medical advice, and not a substitute for professional medical judgment. Independent experimental validation is always required.
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BiohacksAI/Targets/IDE/Compounds

Compounds That Target IDE

insulin degrading enzyme · 72 compounds in BiohacksAI corpus

IDE (insulin degrading enzyme) is a biological target with 72 documented compound interactions in the BiohacksAI corpus. The compounds listed below have been identified through computational analysis of BindingDB binding assay data and PubMed literature. Each interaction is ranked by confidence score reflecting the breadth and strength of experimental evidence. This resource supports research into IDE modulation for therapeutic and biohacking applications.

View IDE target page →UniProt: P14735 ↗
Most Studied Compounds for IDE
1
Curcuma Longa
500+
studies
2
Syzygium Aromaticum
500+
studies
3
Juglans Regia
500+
studies
4
Centella Asiatica
499+
studies
5
Cefmetazole
300+
studies
6
Ethylmaleimide
300+
studies
7
Ginkgo Biloba
299+
studies
8
Biotin
297+
studies
9
Areca Catechu
199+
studies
10
Gedunin
54+
studies
All 50 Compounds — Ranked by Evidence
1
Ebselen
4.74
confidence
2
Rabeprazole
3.18
confidence
3
Biotin
297+
studies
1.39
confidence
4
Ag490
14+
studies
1.10
confidence
5
Cefmetazole
300+
studies
1.10
confidence
6
Aloe Vera
1.00
confidence
7
Centella Asiatica
499+
studies
1.00
confidence
8
Chaenomeles Speciosa
1.00
confidence
9
Citrus Reticulata
1.00
confidence
10
Curcuma Longa
500+
studies
1.00
confidence
11
Gastrodia Elata
1.00
confidence
12
Ginkgo Biloba
299+
studies
1.00
confidence
13
Lilium Lancifolium
1.00
confidence
14
Morus Alba
1.00
confidence
15
Nelumbo Nucifera
1.00
confidence
16
Scutellaria Baicalensis
1.00
confidence
17
Syzygium Aromaticum
500+
studies
1.00
confidence
18
Taraxacum Mongolicum
1.00
confidence
19
Ethylmaleimide
300+
studies
0.69
confidence
20
Gedunin
54+
studies
0.69
confidence
21
Achyranthes Bidentata
0.50
confidence
22
Agastache Rugosa
0.50
confidence
23
Alisma Plantago
0.50
confidence
24
Apis Mellifera
0.50
confidence
25
Arctium Lappa
0.50
confidence
26
Areca Catechu
199+
studies
0.50
confidence
27
Artemisia Annua
0.50
confidence
28
Artemisia Capillaris
0.50
confidence
29
Bombyx Mori
0.50
confidence
30
Bupleurum Chinense
0.50
confidence
31
Carthamus Tinctorius
0.50
confidence
32
Cimicifuga Heracleifolia
0.50
confidence
33
Coix Lacryma
0.50
confidence
34
Commiphora Myrrha
0.50
confidence
35
Cuscuta Chinensis
0.50
confidence
36
Dendrobium Nobile
0.50
confidence
37
Ephedra Sinica
0.50
confidence
38
Eriobotrya Japonica
0.50
confidence
39
Eucommia Ulmoides
0.50
confidence
40
Eupatorium Fortunei
0.50
confidence
41
Forsythia Suspensa
0.50
confidence
42
Fritillaria Cirrhosa
0.50
confidence
43
Gentiana Macrophylla
0.50
confidence
44
Glycine Max
0.50
confidence
45
Juglans Regia
500+
studies
0.50
confidence
46
Leonurus Japonicus
0.50
confidence
47
Ligusticum Chuanxiong
0.50
confidence
48
Lindera Aggregata
0.50
confidence
49
Lobelia Chinensis
0.50
confidence
50
Lonicera Japonica
0.50
confidence

The compounds above were identified through computational analysis of BindingDB binding assay data and PubMed literature for IDE (insulin degrading enzyme). Confidence scores reflect the strength and breadth of experimental evidence.

Explore related resources: IDE target overview · All biological targets · Biological pathways

Data from BindingDB and PubMed. For research purposes only. Not medical advice.