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BiohacksAI/Targets/IDH1/Compounds

Compounds That Target IDH1

isocitrate dehydrogenase (NADP(+)) 1 · 53 compounds in BiohacksAI corpus

IDH1 (isocitrate dehydrogenase (NADP(+)) 1) is a biological target with 53 documented compound interactions in the BiohacksAI corpus. The compounds listed below have been identified through computational analysis of BindingDB binding assay data and PubMed literature. Each interaction is ranked by confidence score reflecting the breadth and strength of experimental evidence. This resource supports research into IDH1 modulation for therapeutic and biohacking applications.

View IDH1 target page →UniProt: CAG38738 ↗
Most Studied Compounds for IDH1
1
Sertraline
1.0k+
studies
2
Simvastatin
1.0k+
studies
3
Dinitrochlorobenzene
300+
studies
4
Lovastatin
300+
studies
5
Tannic Acid
300+
studies
6
2 Chloroadenosine
300+
studies
7
6 Aminonicotinamide
300+
studies
8
Azathioprine
300+
studies
9
Cycloheximide
300+
studies
10
Digitoxigenin
300+
studies
All 50 Compounds — Ranked by Evidence
1
Mangostin
4.14
confidence
2
Licoagrochacone A
3.83
confidence
3
Physalin B
2.64
confidence
4
Ivosidenib
2.40
confidence
5
Enasidenib
2.20
confidence
6
Zuclomiphene
1.79
confidence
7
Licochalcone A
267+
studies
1.61
confidence
8
Mometasone Furoate
292+
studies
1.39
confidence
9
Dinitrochlorobenzene
300+
studies
1.10
confidence
10
Lovastatin
300+
studies
1.10
confidence
11
Methylene Blue
200+
studies
0.69
confidence
12
Sertraline
1.0k+
studies
0.69
confidence
13
Simvastatin
1.0k+
studies
0.69
confidence
14
Tannic Acid
300+
studies
0.69
confidence
15
2 Chloroadenosine
300+
studies
0.69
confidence
16
6 Aminonicotinamide
300+
studies
0.69
confidence
17
Amethopterin
289+
studies
0.69
confidence
18
Anisomycin
247+
studies
0.69
confidence
19
Astemizole
280+
studies
0.69
confidence
20
Azacitidine
298+
studies
0.69
confidence
21
Azacytidine
298+
studies
0.69
confidence
22
Azathioprine
300+
studies
0.69
confidence
23
Calcimycin
216+
studies
0.69
confidence
24
Carbazilquinone
48+
studies
0.69
confidence
25
Chlorhexidine
299+
studies
0.69
confidence
26
Ciclopirox Olaminedrugage
0.69
confidence
27
Clofilium Tosylatedrugage
0.69
confidence
28
Colchinedrugage
0.69
confidence
29
Cycloheximide
300+
studies
0.69
confidence
30
Digitoxigenin
300+
studies
0.69
confidence
31
Digitoxin
300+
studies
0.69
confidence
32
Digoxigenin
300+
studies
0.69
confidence
33
Digoxin
299+
studies
0.69
confidence
34
Ethinyl Estradiol
300+
studies
0.69
confidence
35
Fluspirilene
74+
studies
0.69
confidence
36
Hexachlorophene
300+
studies
0.69
confidence
37
Imatinib Mesylate
300+
studies
0.69
confidence
38
Lanatosides
115+
studies
0.69
confidence
39
Miconazole
298+
studies
0.69
confidence
40
Niclosamideorganic
0.69
confidence
41
Nisoldipinedrugage
0.69
confidence
42
Nortriptyline Hydrochloride
28+
studies
0.69
confidence
43
Propionylpromazine Hydrochloride
2+
studies
0.69
confidence
44
Quinestrol
194+
studies
0.69
confidence
45
Salmeterol Xinafoate
227+
studies
0.69
confidence
46
Streptonigrin
299+
studies
0.69
confidence
47
Strophanthidin
300+
studies
0.69
confidence
48
Thioridazine Hydrochloride
35+
studies
0.69
confidence
49
Triflupromazine Hydrochloride
12+
studies
0.69
confidence
50
Tubercidin
300+
studies
0.69
confidence

The compounds above were identified through computational analysis of BindingDB binding assay data and PubMed literature for IDH1 (isocitrate dehydrogenase (NADP(+)) 1). Confidence scores reflect the strength and breadth of experimental evidence.

Explore related resources: IDH1 target overview · All biological targets · Biological pathways

Data from BindingDB and PubMed. For research purposes only. Not medical advice.