Compounds That Target IRAK1

interleukin 1 receptor associated kinase 1 · 42 compounds in BiohacksAI corpus

IRAK1 (interleukin 1 receptor associated kinase 1) is a biological target with 42 documented compound interactions in the BiohacksAI corpus. The compounds listed below have been identified through computational analysis of BindingDB binding assay data and PubMed literature. Each interaction is ranked by confidence score reflecting the breadth and strength of experimental evidence. This resource supports research into IRAK1 modulation for therapeutic and biohacking applications.

View IRAK1 target page →UniProt: P51617 ↗

Most Studied Compounds for IRAK1

Sorafenib

300+

studies

Crizotinib

298+

studies

Axitinib

298+

studies

Afatinib

297+

studies

Alsterpaullone

12+

studies

All 42 Compounds — Ranked by Evidence

Gefitinib

5.67

confidence

Imatinib

5.47

confidence

Alvocidib

4.52

confidence

Vandetanib

4.30

confidence

Ponatinib

4.26

confidence

Ruxolitinib

4.23

confidence

Bosutinib

4.08

confidence

Bi 2536

4.01

confidence

Quizartinib

3.99

confidence

Pazopanib

3.69

confidence

Neratinib

3.66

confidence

Abemaciclib

3.66

confidence

Nintedanib

3.61

confidence

Canertinib

3.53

confidence

Tae 684

3.43

confidence

Fedratinib

3.40

confidence

Dabrafenib

3.30

confidence

Tandutinib

3.22

confidence

Dovitinib

3.09

confidence

Lestaurtinib

3.04

confidence

Pacritinib

3.04

confidence

Filgotinib

3.04

confidence

R 406

2.83

confidence

Milciclib

2.77

confidence

Pha 665752

2.71

confidence

Crenolanib

2.71

confidence

Kw 2449

2.64

confidence

Ast 487

2.56

confidence

Atuveciclib

2.56

confidence

Mk 5108

2.48

confidence

Gsk 461364

2.40

confidence

Su 014813

2.20

confidence

Rebastinib

2.20

confidence

Encorafenib

2.20

confidence

Cyc 116

2.08

confidence

Ly 3009120

2.08

confidence

Bafetinib

1.95

confidence

Crizotinib

298+

studies

1.10

confidence

Afatinib

297+

studies

0.69

confidence

Alsterpaullone

12+

studies

0.69

confidence

Axitinib

298+

studies

0.69

confidence

Sorafenib

300+

studies

0.69

confidence

The compounds above were identified through computational analysis of BindingDB binding assay data and PubMed literature for IRAK1 (interleukin 1 receptor associated kinase 1). Confidence scores reflect the strength and breadth of experimental evidence.

Explore related resources: IRAK1 target overview · All biological targets · Biological pathways

Data from BindingDB and PubMed. For research purposes only. Not medical advice.