BETABiohacksAI is a research tool for informational purposes only. All outputs are computational hypothesis candidates — not confirmed mechanisms, not medical advice, and not a substitute for professional medical judgment. Independent experimental validation is always required.
BiohacksAI is an evolving research platform. New compounds and evidence are added continuously.
B

Compounds That Target IRAK3

interleukin 1 receptor associated kinase 3 · 36 compounds in BiohacksAI corpus

IRAK3 (interleukin 1 receptor associated kinase 3) is a biological target with 36 documented compound interactions in the BiohacksAI corpus. The compounds listed below have been identified through computational analysis of BindingDB binding assay data and PubMed literature. Each interaction is ranked by confidence score reflecting the breadth and strength of experimental evidence. This resource supports research into IRAK3 modulation for therapeutic and biohacking applications.

Most Studied Compounds for IRAK3
298+
studies
All 36 Compounds — Ranked by Evidence
1
Gefitinib
5.67
confidence
2
Foretinib
4.34
confidence
3
Tozasertib
4.33
confidence
4
Midostaurin
3.85
confidence
5
Pazopanib
3.69
confidence
6
Nintedanib
3.61
confidence
7
Canertinib
3.53
confidence
8
Bms 387032
3.47
confidence
9
Tae 684
3.43
confidence
10
Fedratinib
3.40
confidence
11
Gilteritinib
3.40
confidence
12
Mln 8054
3.33
confidence
13
Sgi 1776
3.26
confidence
14
Tandutinib
3.22
confidence
15
Omipalisib
3.14
confidence
16
Jnj 7706621
3.09
confidence
17
Lestaurtinib
3.04
confidence
18
Pacritinib
3.04
confidence
19
Defosbarasertib
2.89
confidence
20
R 406
2.83
confidence
21
K 252a
2.83
confidence
22
Milciclib
2.77
confidence
23
Pha 665752
2.71
confidence
24
Crenolanib
2.71
confidence
25
Azd 5438
2.71
confidence
26
Kw 2449
2.64
confidence
27
Zotiraciclib
2.56
confidence
28
Mk 5108
2.48
confidence
29
Gsk 461364
2.40
confidence
30
Su 014813
2.20
confidence
31
Cyc 116
2.08
confidence
32
Mk 2461
2.08
confidence
33
Fostamatinib
2.08
confidence
34
Gsk 1059615
1.95
confidence
298+
studies
1.10
confidence
36
Pictilisibdrugage
0.69
confidence

The compounds above were identified through computational analysis of BindingDB binding assay data and PubMed literature for IRAK3 (interleukin 1 receptor associated kinase 3). Confidence scores reflect the strength and breadth of experimental evidence.

Explore related resources: IRAK3 target overview · All biological targets · Biological pathways

Data from BindingDB and PubMed. For research purposes only. Not medical advice.