Compounds That Target JAK2

Janus kinase 2 · 211 compounds in BiohacksAI corpus

JAK2 (Janus kinase 2) is a biological target with 211 documented compound interactions in the BiohacksAI corpus. The compounds listed below have been identified through computational analysis of BindingDB binding assay data and PubMed literature. Each interaction is ranked by confidence score reflecting the breadth and strength of experimental evidence. This resource supports research into JAK2 modulation for therapeutic and biohacking applications.

View JAK2 target page →UniProt: O60674 ↗

All 50 Compounds — Ranked by Evidence

Erlotinib

5.55

confidence

Tofacitinib

4.65

confidence

Alvocidib

4.52

confidence

Foretinib

4.34

confidence

Tozasertib

4.33

confidence

Ponatinib

4.26

confidence

Ruxolitinib

4.23

confidence

Ceritinib

4.19

confidence

Bosutinib

4.08

confidence

Midostaurin

3.85

confidence

Brigatinib

3.81

confidence

Pazopanib

3.69

confidence

Nintedanib

3.61

confidence

Baricitinib

3.56

confidence

Pelitinib

3.50

confidence

6bio

3.50

confidence

Tae 684

3.43

confidence

Fedratinib

3.40

confidence

Dabrafenib

3.30

confidence

Entrectinib

3.18

confidence

Sulfuretin

3.14

confidence

Dovitinib

3.09

confidence

Jnj 7706621

3.09

confidence

At 9283

3.09

confidence

Upadacitinib

3.09

confidence

Lestaurtinib

3.04

confidence

Pacritinib

3.04

confidence

Filgotinib

3.04

confidence

Adavosertib

3.04

confidence

Spebrutinib

3.04

confidence

Repotrectinib

3.00

confidence

Danusertib

2.94

confidence

Momelotinib

2.89

confidence

Go 6976

2.89

confidence

R 406

2.83

confidence

Infigratinib

2.77

confidence

Pha 665752

2.71

confidence

Kw 2449

2.64

confidence

Ast 487

2.56

confidence

Zotiraciclib

2.56

confidence

Defactinib

2.48

confidence

Mk 5108

2.48

confidence

Lorlatinib

2.48

confidence

Entospletinib

2.48

confidence

Deucravacitinib

2.48

confidence

Azd 7762

2.30

confidence

Bms 754807

2.30

confidence

Azd 1480

2.30

confidence

Berzosertib

2.30

confidence

Reversine

2.30

confidence

The compounds above were identified through computational analysis of BindingDB binding assay data and PubMed literature for JAK2 (Janus kinase 2). Confidence scores reflect the strength and breadth of experimental evidence.

Explore related resources: JAK2 target overview · All biological targets · Biological pathways

Data from BindingDB and PubMed. For research purposes only. Not medical advice.