Compounds That Target JAK3

Janus kinase 3 · 77 compounds in BiohacksAI corpus

JAK3 (Janus kinase 3) is a biological target with 77 documented compound interactions in the BiohacksAI corpus. The compounds listed below have been identified through computational analysis of BindingDB binding assay data and PubMed literature. Each interaction is ranked by confidence score reflecting the breadth and strength of experimental evidence. This resource supports research into JAK3 modulation for therapeutic and biohacking applications.

View JAK3 target page →UniProt: P52333 ↗

All 50 Compounds — Ranked by Evidence

Erlotinib

5.55

confidence

Ibrutinib

4.86

confidence

Tofacitinib

4.65

confidence

Alvocidib

4.52

confidence

Tozasertib

4.33

confidence

Dactolisib

4.25

confidence

Ruxolitinib

4.23

confidence

Palbociclib

4.22

confidence

Ceritinib

4.19

confidence

Bosutinib

4.08

confidence

Midostaurin

3.85

confidence

Pazopanib

3.69

confidence

Neratinib

3.66

confidence

Nintedanib

3.61

confidence

Baricitinib

3.56

confidence

Canertinib

3.53

confidence

Pelitinib

3.50

confidence

Tae 684

3.43

confidence

Fedratinib

3.40

confidence

Sp 600125

3.22

confidence

Acalabrutinib

3.22

confidence

Entrectinib

3.18

confidence

Sulfuretin

3.14

confidence

Dacomitinib Anhydrous

3.14

confidence

Dovitinib

3.09

confidence

Jnj 7706621

3.09

confidence

At 9283

3.09

confidence

Upadacitinib

3.09

confidence

Lestaurtinib

3.04

confidence

Pacritinib

3.04

confidence

Filgotinib

3.04

confidence

Adavosertib

3.04

confidence

Spebrutinib

3.04

confidence

Ruboxistaurin

2.94

confidence

Momelotinib

2.89

confidence

R 406

2.83

confidence

Sotrastaurin

2.77

confidence

Ritlecitinib

2.77

confidence

Staurosporinone

2.77

confidence

Pha 665752

2.71

confidence

Kw 2449

2.64

confidence

Ast 487

2.56

confidence

Zanubrutinib

2.56

confidence

Defactinib

2.48

confidence

Deucravacitinib

2.48

confidence

Azd 1480

2.30

confidence

Reversine

2.30

confidence

Vs 5584

2.30

confidence

Su 014813

2.20

confidence

Decernotinib

2.20

confidence

The compounds above were identified through computational analysis of BindingDB binding assay data and PubMed literature for JAK3 (Janus kinase 3). Confidence scores reflect the strength and breadth of experimental evidence.

Explore related resources: JAK3 target overview · All biological targets · Biological pathways

Data from BindingDB and PubMed. For research purposes only. Not medical advice.