BETABiohacksAI is a research tool for informational purposes only. All outputs are computational hypothesis candidates — not confirmed mechanisms, not medical advice, and not a substitute for professional medical judgment. Independent experimental validation is always required.
BiohacksAI is an evolving scientific literature platform. New compounds and evidence are indexed continuously.
B
○
BiohacksAI/Targets/KAPPA-TYPE/Compounds

Compounds That Target KAPPA-TYPE

Kappa-type opioid receptor (human) · 60 compounds in BiohacksAI corpus

KAPPA-TYPE (Kappa-type opioid receptor (human)) is a biological target with 60 documented compound interactions in the BiohacksAI corpus. The compounds listed below have been identified through computational analysis of BindingDB binding assay data and PubMed literature. Each interaction is ranked by confidence score reflecting the breadth and strength of experimental evidence. This resource supports research into KAPPA-TYPE modulation for therapeutic and biohacking applications.

View KAPPA-TYPE target page →UniProt: P41145 ↗
Most Studied Compounds for KAPPA-TYPE
1
Sertraline
1.0k+
studies
2
Quetiapine
994+
studies
3
Aprindine
300+
studies
4
Encainide
300+
studies
5
Eserine
300+
studies
6
Etorphine
300+
studies
7
Fentanyl
300+
studies
8
Phentolamine
300+
studies
9
Econazole
299+
studies
10
Domperidone
299+
studies
All 50 Compounds — Ranked by Evidence
1
Morphinedrugage
1.95
confidence
2
Clotrimazoleheterocyclic
1.39
confidence
3
Econazole
299+
studies
1.39
confidence
4
Astemizole
280+
studies
1.10
confidence
5
Disulfiram
297+
studies
1.10
confidence
6
Domperidone
299+
studies
1.10
confidence
7
Levorphanol
297+
studies
1.10
confidence
8
Miconazole
298+
studies
1.10
confidence
9
Nalbuphineheterocyclic
1.10
confidence
10
Naloxoneheterocyclic
1.10
confidence
11
Ritonavir
298+
studies
1.10
confidence
12
Mianserin
299+
studies
0.69
confidence
13
Quetiapine
994+
studies
0.69
confidence
14
Sertraline
1.0k+
studies
0.69
confidence
15
Amitriptyline
299+
studies
0.69
confidence
16
Amoxapine
259+
studies
0.69
confidence
17
Aprindine
300+
studies
0.69
confidence
18
Benzethonium
96+
studies
0.69
confidence
19
Butorphanol
299+
studies
0.69
confidence
20
Chlorhexidine
299+
studies
0.69
confidence
21
Cilostazolheterocyclic
0.69
confidence
22
Clonidineheterocyclic
0.69
confidence
23
Codeineheterocyclic
0.69
confidence
24
Cyproterone
299+
studies
0.69
confidence
25
Danazol
298+
studies
0.69
confidence
26
Dextromethorphan
296+
studies
0.69
confidence
27
Dibucaine
299+
studies
0.69
confidence
28
Encainide
300+
studies
0.69
confidence
29
Eserine
300+
studies
0.69
confidence
30
Etorphine
300+
studies
0.69
confidence
31
Fentanyl
300+
studies
0.69
confidence
32
Flecainide
297+
studies
0.69
confidence
33
Fluspirilene
74+
studies
0.69
confidence
34
Guanfacine
294+
studies
0.69
confidence
35
Hydrocodone
294+
studies
0.69
confidence
36
Hydroxyzine
298+
studies
0.69
confidence
37
Isoetharine
112+
studies
0.69
confidence
38
Lidoflazine
278+
studies
0.69
confidence
39
Loratadine
296+
studies
0.69
confidence
40
Loxapine
225+
studies
0.69
confidence
41
Lynestrenol
299+
studies
0.69
confidence
42
Meclizine
121+
studies
0.69
confidence
43
Meperidine
297+
studies
0.69
confidence
44
Nebivololdrugage
0.69
confidence
45
Nefopamheterocyclic
0.69
confidence
46
Nortriptyline
295+
studies
0.69
confidence
47
Nylidrin
90+
studies
0.69
confidence
48
Oxycodone
298+
studies
0.69
confidence
49
Perphenazine
297+
studies
0.69
confidence
50
Phentolamine
300+
studies
0.69
confidence

The compounds above were identified through computational analysis of BindingDB binding assay data and PubMed literature for KAPPA-TYPE (Kappa-type opioid receptor (human)). Confidence scores reflect the strength and breadth of experimental evidence.

Explore related resources: KAPPA-TYPE target overview · All biological targets · Biological pathways

Data from BindingDB and PubMed. For research purposes only. Not medical advice.