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Compounds That Target KIT

KIT proto-oncogene, receptor tyrosine kinase · 198 compounds in BiohacksAI corpus

KIT (KIT proto-oncogene, receptor tyrosine kinase) is a biological target with 198 documented compound interactions in the BiohacksAI corpus. The compounds listed below have been identified through computational analysis of BindingDB binding assay data and PubMed literature. Each interaction is ranked by confidence score reflecting the breadth and strength of experimental evidence. This resource supports research into KIT modulation for therapeutic and biohacking applications.

Most Studied Compounds for KIT
300+
studies
300+
studies
298+
studies
246+
studies
All 50 Compounds — Ranked by Evidence
1
Gefitinib
5.67
confidence
2
Erlotinib
5.55
confidence
3
Imatinib
5.47
confidence
4
Alvocidib
4.52
confidence
5
Cabozantinib
4.39
confidence
6
Foretinib
4.34
confidence
7
Tozasertib
4.33
confidence
8
Vandetanib
4.30
confidence
9
Ponatinib
4.26
confidence
10
Ruxolitinib
4.23
confidence
11
Ceritinib
4.19
confidence
12
Nilotinib
4.17
confidence
300+
studies
4.17
confidence
14
Bosutinib
4.08
confidence
15
Doramapimod
4.06
confidence
16
Quizartinib
3.99
confidence
17
Semaxanib
3.93
confidence
18
Midostaurin
3.85
confidence
19
Brigatinib
3.81
confidence
20
Pazopanib
3.69
confidence
21
Vatalanib
3.69
confidence
300+
studies
3.66
confidence
23
Nintedanib
3.61
confidence
24
Regorafenib
3.56
confidence
25
Canertinib
3.53
confidence
26
Tae 684
3.43
confidence
27
Pexidartinib
3.43
confidence
28
Fedratinib
3.40
confidence
29
Bms 777607
3.37
confidence
30
Linifanib
3.33
confidence
31
Saracatinib
3.33
confidence
298+
studies
3.22
confidence
33
Tandutinib
3.22
confidence
34
Dovitinib
3.09
confidence
35
Jnj 7706621
3.09
confidence
36
Dasatinib Anhydrous
3.09
confidence
37
Lestaurtinib
3.04
confidence
38
Ruboxistaurin
2.94
confidence
39
Danusertib
2.94
confidence
40
Defosbarasertib
2.89
confidence
41
Barasertib
2.89
confidence
246+
studies
2.83
confidence
43
R 406
2.83
confidence
44
Cediranib
2.83
confidence
45
Milciclib
2.77
confidence
46
Infigratinib
2.77
confidence
47
Masitinib
2.77
confidence
48
Pha 665752
2.71
confidence
49
Plx 4720
2.71
confidence
50
Enmd 2076
2.71
confidence

The compounds above were identified through computational analysis of BindingDB binding assay data and PubMed literature for KIT (KIT proto-oncogene, receptor tyrosine kinase). Confidence scores reflect the strength and breadth of experimental evidence.

Explore related resources: KIT target overview · All biological targets · Biological pathways

Data from BindingDB and PubMed. For research purposes only. Not medical advice.