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Compounds That Target LCK

LCK proto-oncogene, Src family tyrosine kinase · 109 compounds in BiohacksAI corpus

LCK (LCK proto-oncogene, Src family tyrosine kinase) is a biological target with 109 documented compound interactions in the BiohacksAI corpus. The compounds listed below have been identified through computational analysis of BindingDB binding assay data and PubMed literature. Each interaction is ranked by confidence score reflecting the breadth and strength of experimental evidence. This resource supports research into LCK modulation for therapeutic and biohacking applications.

All 50 Compounds — Ranked by Evidence
1
Tamoxifen
5.88
confidence
2
Gefitinib
5.67
confidence
3
Erlotinib
5.55
confidence
4
Imatinib
5.47
confidence
5
Elliptecine
5.21
confidence
6
Sb 203580
4.92
confidence
7
Ibrutinib
4.86
confidence
8
Tofacitinib
4.65
confidence
9
Alvocidib
4.52
confidence
10
Nelfinavir
4.51
confidence
11
Cabozantinib
4.39
confidence
12
Foretinib
4.34
confidence
13
Tozasertib
4.33
confidence
14
Vandetanib
4.30
confidence
15
Ponatinib
4.26
confidence
16
Caffeic Acid Phenethyl Ester
4.25
confidence
17
Ceritinib
4.19
confidence
18
Nilotinib
4.17
confidence
19
Bosutinib
4.08
confidence
20
Doramapimod
4.06
confidence
21
Quizartinib
3.99
confidence
22
Midostaurin
3.85
confidence
23
Brigatinib
3.81
confidence
24
Pazopanib
3.69
confidence
25
Neratinib
3.66
confidence
26
Nintedanib
3.61
confidence
27
Canertinib
3.53
confidence
28
Pelitinib
3.50
confidence
29
Tae 684
3.43
confidence
30
Pexidartinib
3.43
confidence
31
Fedratinib
3.40
confidence
32
Dobutamine
3.37
confidence
33
Bms 777607
3.37
confidence
34
Mln 8054
3.33
confidence
35
Saracatinib
3.33
confidence
36
Dabrafenib
3.30
confidence
37
Neflamapimod
3.30
confidence
38
Alisertib
3.30
confidence
39
Tandutinib
3.22
confidence
40
Dorsomorphin
3.14
confidence
41
Dacomitinib Anhydrous
3.14
confidence
42
Dovitinib
3.09
confidence
43
At 9283
3.09
confidence
44
Dasatinib Anhydrous
3.09
confidence
45
Upadacitinib
3.09
confidence
46
Lestaurtinib
3.04
confidence
47
Pacritinib
3.04
confidence
48
Ruboxistaurin
2.94
confidence
49
Danusertib
2.94
confidence
50
Defosbarasertib
2.89
confidence

The compounds above were identified through computational analysis of BindingDB binding assay data and PubMed literature for LCK (LCK proto-oncogene, Src family tyrosine kinase). Confidence scores reflect the strength and breadth of experimental evidence.

Explore related resources: LCK target overview · All biological targets · Biological pathways

Data from BindingDB and PubMed. For research purposes only. Not medical advice.