Compounds That Target LRRK2

leucine rich repeat kinase 2 · 134 compounds in BiohacksAI corpus

LRRK2 (leucine rich repeat kinase 2) is a biological target with 134 documented compound interactions in the BiohacksAI corpus. The compounds listed below have been identified through computational analysis of BindingDB binding assay data and PubMed literature. Each interaction is ranked by confidence score reflecting the breadth and strength of experimental evidence. This resource supports research into LRRK2 modulation for therapeutic and biohacking applications.

View LRRK2 target page →UniProt: Q5S007 ↗

Most Studied Compounds for LRRK2

Curcuma Longa

500+

studies

Centella Asiatica

499+

studies

Ginkgo Biloba

299+

studies

Axitinib

298+

studies

Ha1077

11+

studies

All 51 Compounds — Ranked by Evidence

Erlotinib

5.55

confidence

Tofacitinib

4.65

confidence

Alvocidib

4.52

confidence

Ponatinib

4.26

confidence

Ruxolitinib

4.23

confidence

Bosutinib

4.08

confidence

Midostaurin

3.85

confidence

Brigatinib

3.81

confidence

Nintedanib

3.61

confidence

Canertinib

3.53

confidence

Y 27632

3.47

confidence

Tae 684

3.43

confidence

Fedratinib

3.40

confidence

Adenine

3.22

confidence

Dovitinib

3.09

confidence

Lestaurtinib

3.04

confidence

Ruboxistaurin

2.94

confidence

R 406

2.83

confidence

Kw 2449

2.64

confidence

Mli 2

2.64

confidence

Ast 487

2.56

confidence

Su 014813

2.20

confidence

Rebastinib

2.20

confidence

Gsk 269962a

2.08

confidence

Dnl 201

1.79

confidence

Axitinib

298+

studies

1.10

confidence

Ha1077

11+

studies

1.10

confidence

Lonicera Japonica

1.00

confidence

Agastache Rugosa

1.00

confidence

Allium Tuberosum

1.00

confidence

Aloe Vera

1.00

confidence

Artemisia Argyi

1.00

confidence

Artemisia Capillaris

1.00

confidence

Aster Tataricus

1.00

confidence

Atractylodes Macrocephala

1.00

confidence

Bupleurum Chinense

1.00

confidence

Carthamus Tinctorius

1.00

confidence

Centella Asiatica

499+

studies

1.00

confidence

Chaenomeles Speciosa

1.00

confidence

Citrus Reticulata

1.00

confidence

Curcuma Longa

500+

studies

1.00

confidence

Cuscuta Chinensis

1.00

confidence

Cynomorium Songaricum

1.00

confidence

Ephedra Sinica

1.00

confidence

Fritillaria Cirrhosa

1.00

confidence

Gastrodia Elata

1.00

confidence

Ginkgo Biloba

299+

studies

1.00

confidence

Ligusticum Chuanxiong

1.00

confidence

Litchi Chinensis

1.00

confidence

Lobelia Chinensis

1.00

confidence

Pictilisibdrugage

0.69

confidence

The compounds above were identified through computational analysis of BindingDB binding assay data and PubMed literature for LRRK2 (leucine rich repeat kinase 2). Confidence scores reflect the strength and breadth of experimental evidence.

Explore related resources: LRRK2 target overview · All biological targets · Biological pathways

Data from BindingDB and PubMed. For research purposes only. Not medical advice.